Lineage for Family b.36.1.1: PDZ domain

  1. Root: SCOPe 2.06
  2. 2017114Class b: All beta proteins [48724] (177 folds)
  3. 2048292Fold b.36: PDZ domain-like [50155] (1 superfamily)
    contains barrel, partly opened; n*=4, S*=8; meander; capped by alpha-helix
  4. 2048293Superfamily b.36.1: PDZ domain-like [50156] (7 families) (S)
    peptide-binding domain
  5. 2048294Family b.36.1.1: PDZ domain [50157] (47 protein domains)
    Pfam PF00595

Protein Domains:

  1. 2048295Afadin [141269] (1 species)
  2. 2048299Alpha-actinin-2 associated LIM protein [110178] (1 species)
  3. 2048302Amyloid beta A4 precursor protein-binding family A member 1 (APBA1, X11) [141282] (1 species)
  4. 2048311Cask/Lin-2 [50160] (1 species)
  5. 2048315Channel associated protein of synapse-110 [141273] (1 species)
    Discs large homolog 2, PSD-93
  6. 2048318Discs large 5 protein KIAA0583 [101725] (1 species)
  7. 2048321Discs large protein homolog [50158] (1 species)
  8. 2048327DNA Regulating synaptic membrane exocytosis protein 2, RIMS2 [117176] (1 species)
  9. 2048330Enigma homolog ENH [117174] (1 species)
  10. 2048333Erbin [82085] (1 species)
  11. 2048340Glutamate receptor interacting protein [82083] (2 species)
    1. 2048341Species Mouse (Mus musculus) [TaxId:10090] [110177] (1 PDB entry)
      Uniprot Q925T6 461-570
    2. 2048343Species Norway rat (Rattus norvegicus) [TaxId:10116] [82084] (3 PDB entries)
  12. 2048348Glutamate receptor interacting protein 2, GRIP2 (KIAA1719) [110180] (1 species)
  13. 2048352Glutamate receptor-interacting protein 1, GRIP1 [101717] (1 species)
  14. 2048357GTPase-binding domain of the cell polarity protein par6 (Par-6B) [89315] (2 species)
    1. 2048358Species Fruit fly (Drosophila melanogaster) [TaxId:7227] [101716] (3 PDB entries)
      Uniprot O97111 156-253; Cg5884-pa
    2. 2048362Species Mouse (Mus musculus) [TaxId:10090] [89316] (1 PDB entry)
  15. 2048365Harmonin [110182] (2 species)
    1. 2048366Species Human (Homo sapiens) [TaxId:9606] [141263] (1 PDB entry)
      Uniprot Q9Y6N9 201-301
    2. 2048368Species Mouse (Mus musculus) [TaxId:10090] [110183] (1 PDB entry)
      Uniprot Q9ES64 741-850
  16. 2048370hypothetical PDZ domain containing protein Uqcrc2 (4930408O21Rik) [117184] (1 species)
  17. 2048373Hypothetical protein KIAA0559 [101727] (1 species)
  18. 2048376Hypothetical protein KIAA1095 [101723] (1 species)
  19. 2048380Hypothetical protein KIAA1849 [101729] (1 species)
  20. 2048383Inad [63756] (1 species)
  21. 2048387KIAA1526 protein [101721] (1 species)
  22. 2048392Maguk p55 subfamily member 5 [141275] (1 species)
  23. 2048395Membrane associated guanylate kinase inverted-2 (MAGI-2, KIAA0705) [101719] (1 species)
  24. 2048402Multiple PDZ domain protein [141267] (1 species)
  25. 2048412Na+/H+ exchanger regulatory factor, NHERF [63754] (1 species)
  26. 2048418Neurabin-i [141277] (1 species)
  27. 2048421Neuronal nitric oxide synthase, NNOS [50166] (1 species)
  28. 2048426Partitioning-defective 3-like protein, PAR3-L (RIKEN cDNA 2810455b10) [117178] (1 species)
  29. 2048429PDZ domain containing protein 11, Pdzk11 [117182] (1 species)
  30. 2048432PDZ-LIM protein mystique [110186] (1 species)
  31. 2048435Phosphatase hPTP1e [50168] (2 species)
    1. 2048436Species Human (Homo sapiens) [TaxId:9606] [50169] (7 PDB entries)
    2. 2048449Species Mouse (Mus musculus) [TaxId:10090] [74930] (3 PDB entries)
  32. 2048453Presynaptic protein sap97 [141284] (1 species)
    PSD-95 homologue
  33. 2048456Regulating synaptic membrane exocytosis protein 1, RIMS1 [141279] (2 species)
    1. 2048457Species Human (Homo sapiens) [TaxId:9606] [141281] (1 PDB entry)
      Uniprot Q86UR5 585-694
    2. 2048459Species Norway rat (Rattus norvegicus) [TaxId:10116] [141280] (1 PDB entry)
      Uniprot Q9JIR4 597-705
  34. 2048461Regulator of G-protein signaling 3, RGS3 [117180] (2 species)
    1. 2048462Species Human (Homo sapiens) [TaxId:9606] [141264] (1 PDB entry)
      Uniprot P49796 300-376
    2. 2048465Species Mouse (Mus musculus) [TaxId:10090] [117181] (1 PDB entry)
      Uniprot Q9DC04 18-94
  35. 2048467Rhophilin-2 [110184] (1 species)
  36. 2048470Scribble (KIAA0147) [101731] (1 species)
  37. 2048477Segment polarity protein dishevelled homolog Dvl-2 [89313] (3 species)
    1. 2048478Species African clawed frog (Xenopus laevis) [TaxId:8355] [89314] (2 PDB entries)
    2. 2048486Species Human (Homo sapiens) [TaxId:9606] [188234] (5 PDB entries)
    3. 2048496Species Mouse (Mus musculus) [TaxId:10090] [101715] (1 PDB entry)
  38. 2048498Shank1, PDZ domain [101733] (1 species)
    SH3 and multiple ankyrin repeat domains protein 1
  39. 2048515Synapse-associated protein 102 [101713] (1 species)
  40. 2048519Synaptic protein PSD-95 [50162] (2 species)
    Synonym: synapse associated protein 90, sap90
    duplication: contains three PDZ domains
    1. 2048520Species Human (Homo sapiens) [TaxId:9606] [74932] (1 PDB entry)
    2. 2048522Species Norway rat (Rattus norvegicus) [TaxId:10116] [50163] (12 PDB entries)
      Uniprot P31016 62-154
  41. 2048531Syntaxin binding protein 4 [141271] (1 species)
  42. 2048534Syntenin 1 [89311] (1 species)
  43. 2048569Syntrophin [50164] (1 species)
  44. 2048573Tight junction protein ZO-2, Tjp2 [141265] (1 species)
  45. 2048576Tyrosine-protein phosphatase non-receptor type 4, PTPN4 [141286] (1 species)
  46. 2048585Zasp (Cypher, Oracle 1) [101735] (2 species)
    1. 2048586Species Human (Homo sapiens) [TaxId:9606] [101736] (1 PDB entry)
    2. 2048588Species Mouse (Mus musculus) [TaxId:10090] [117173] (1 PDB entry)
      Uniprot Q9D130 1-83
  47. 2048590automated matches [190055] (7 species)
    not a true protein
    1. 2048591Species African clawed frog (Xenopus laevis) [TaxId:8355] [187076] (1 PDB entry)
    2. 2048594Species Fruit fly (Drosophila melanogaster) [TaxId:7227] [255425] (2 PDB entries)
    3. 2048597Species Homo sapiens, influenza a virus [TaxId:9606] [193650] (1 PDB entry)
    4. 2048599Species Human (Homo sapiens) [TaxId:9606] [187785] (40 PDB entries)
    5. 2048667Species Mouse (Mus musculus) [TaxId:10090] [189198] (6 PDB entries)
    6. 2048682Species Norway rat (Rattus norvegicus) [TaxId:10116] [186775] (9 PDB entries)
    7. 2283113Species Homo sapiens [TaxId:9606] [326414] (1 PDB entry)

More info for Family b.36.1.1: PDZ domain

Timeline for Family b.36.1.1: PDZ domain: