Lineage for Family b.34.2.1: SH3-domain

  1. Root: SCOPe 2.03
  2. 1287432Class b: All beta proteins [48724] (174 folds)
  3. 1309919Fold b.34: SH3-like barrel [50036] (21 superfamilies)
    barrel, partly opened; n*=4, S*=8; meander
    the last strand is interrupted by a turn of 3-10 helix
  4. 1310020Superfamily b.34.2: SH3-domain [50044] (2 families) (S)
  5. 1310021Family b.34.2.1: SH3-domain [50045] (40 proteins)

Proteins:

  1. 131002253BP2 [50078] (1 species)
  2. 1310025Abl tyrosine kinase, SH3 domain [50052] (2 species)
    1. 1310026Species Human (Homo sapiens) [TaxId:9606] [50054] (6 PDB entries)
    2. 1310036Species Mouse (Mus musculus) [TaxId:10090] [50053] (3 PDB entries)
  3. 1310041Actin binding protein ABP1 [74920] (1 species)
  4. 1310045alpha-Spectrin, SH3 domain [50058] (1 species)
  5. 1310076Amphiphysin 2 [50080] (1 species)
    synonyms: Myc box dependent interacting protein 1, bin1
  6. 1310082BAI1-associated protein 2-like 1 (RIKEN cDNA 1300006m19) [110161] (1 species)
  7. 1310085Bruton's tyrosine kinase [50068] (2 species)
    1. 1310086Species Human (Homo sapiens) [TaxId:9606] [50069] (3 PDB entries)
    2. 1310090Species Mouse (Mus musculus) [TaxId:10090] [159018] (2 PDB entries)
  8. 1310093BZZ1 [141188] (1 species)
  9. 1310096C-Crk, N-terminal SH3 domain [50046] (1 species)
  10. 1310107c-src protein tyrosine kinase [50064] (3 species)
    1. 1310108Species Avian sarcoma virus [TaxId:11876] [50067] (2 PDB entries)
      v-src
    2. 1310111Species Chicken (Gallus gallus) [TaxId:9031] [50066] (9 PDB entries)
    3. 1310121Species Human (Homo sapiens) [TaxId:9606] [50065] (5 PDB entries)
  11. 1310127Carboxyl-terminal src kinase (csk) [74654] (2 species)
    1. 1310128Species Human (Homo sapiens) [TaxId:9606] [74658] (2 PDB entries)
    2. 1310139Species Mouse (Mus musculus) [TaxId:10090] [74655] (1 PDB entry)
  12. 1310141EPS8 SH3 domain [50082] (1 species)
  13. 1310149Fyn proto-oncogene tyrosine kinase, SH3 domain [50048] (1 species)
  14. 1310173Fyn-binding protein (T-cell adapter protein adap) [101681] (1 species)
  15. 1310176Grb2-related adaptor protein 2 (Mona/Gads) [89293] (1 species)
  16. 1310182Growth factor receptor-bound protein 2 (GRB2), N- and C-terminal domains [50070] (3 species)
    1. 1310183Species Caenorhabditis elegans, SEM-5 [TaxId:6239] [50073] (5 PDB entries)
      Sex muscle abnormal protein 5
    2. 1310192Species Human (Homo sapiens) [TaxId:9606] [50071] (6 PDB entries)
    3. 1310203Species Mouse (Mus musculus) [TaxId:10090] [50072] (5 PDB entries)
  17. 1310209Hemapoetic cell kinase Hck [50062] (1 species)
  18. 1310252Hypothetical protein Baa76854.1 (KIAA1010) [101671] (1 species)
  19. 1310256Hypothetical protein YFR024c [101679] (1 species)
  20. 1310259IL-2 inducible T-cell (Itc) kinase [50060] (1 species)
  21. 1310262Intersectin 2 (KIAA1256) [101669] (1 species)
  22. 1310269Kalirin-9a [117147] (1 species)
  23. 1310272Melanoma inhibitory activity protein [63746] (1 species)
  24. 1310278Nck-2 [159019] (1 species)
  25. 1310281Olygophrenin-1 like protein (KIAA0621) [101673] (1 species)
  26. 1310284p47pox (neutrophil cytosolic factor 1) [89295] (1 species)
  27. 1310296p56-lck tyrosine kinase, SH3 domain [50076] (1 species)
  28. 1310308p67phox [74922] (1 species)
  29. 1310311Peroxisomal membrane protein Pex13p [82055] (1 species)
  30. 1310320Phosphatidylinositol 3-kinase (p85-alpha subunit, pi3k), SH3 domain [50055] (2 species)
    1. 1310321Species Cow (Bos taurus) [TaxId:9913] [50057] (2 PDB entries)
    2. 1310324Species Human (Homo sapiens) [TaxId:9606] [50056] (3 PDB entries)
  31. 1310328Phospholipase C, SH3 domain [50074] (1 species)
  32. 1310332Psd-95 [69248] (1 species)
    associates with a guanylate kinase domain
  33. 1310338Rac/CDC42 GEF 6 [101677] (1 species)
  34. 1310341RIM binding protein 2, RIMBP2 [117149] (1 species)
  35. 1310344SH3 domain from nebulin [50050] (1 species)
  36. 1310348SH3-like domain of the L-type calcium channel [110158] (2 species)
    1. 1310349Species Norway rat (Rattus norvegicus) [TaxId:10116] [110160] (5 PDB entries)
      Uniprot P54287 38-362
    2. 1310358Species Rabbit (Oryctolagus cuniculus) [TaxId:9986] [110159] (4 PDB entries)
      Uniprot P54288
  37. 1310363Signal transducing adaptor molecule Stam2 [101675] (1 species)
  38. 1310366tyrosine kinase tec [69246] (1 species)
  39. 1310369Vav N-terminal SH3 domain [63744] (1 species)
  40. 1310377automated matches [190043] (5 species)
    not a true protein
    1. 1310378Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [186765] (3 PDB entries)
    2. 1310384Species Chicken (Gallus gallus) [TaxId:9031] [187080] (5 PDB entries)
    3. 1310393Species Human (Homo sapiens) [TaxId:9606] [187799] (15 PDB entries)
    4. 1310410Species Mouse (Mus musculus) [TaxId:10090] [187043] (3 PDB entries)
    5. 1310417Species Norway rat (Rattus norvegicus) [TaxId:10116] [187407] (7 PDB entries)

More info for Family b.34.2.1: SH3-domain

Timeline for Family b.34.2.1: SH3-domain: