SCOP 1.65: Family b.34.2.1: SH3-domain

Lineage for Family b.34.2.1: SH3-domain

1. Root: SCOP 1.65

2. Class b: All beta proteins [48724] (126 folds)

3. Fold b.34: SH3-like barrel [50036] (13 superfamilies)
   barrel, partly opened; n*=4, S*=8; meander
   the last strand is interrupted by a turn of 3-10 helix

4. Superfamily b.34.2: SH3-domain [50044] (1 family)

5. Family b.34.2.1: SH3-domain [50045] (26 proteins)

Proteins:

1. 53BP2 [50078] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [50079] (1 PDB entry)

2. Abl tyrosine kinase, SH3 domain [50052] (2 species)

   1. Species Human (Homo sapiens) [TaxId:9606] [50054] (4 PDB entries)

   2. Species Mouse (Mus musculus) [TaxId:10090] [50053] (4 PDB entries)

3. Actin binding protein ABP1 [74920] (1 species)

   • Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [74921] (1 PDB entry)

4. alpha-Spectrin, SH3 domain [50058] (1 species)

   • Species Chicken (Gallus gallus) [TaxId:9031] [50059] (17 PDB entries)

5. Amphiphysin 2 [50080] (1 species)

   • Species Rat (Rattus norvegicus) [TaxId:10116] [50081] (1 PDB entry)

6. Bruton's tyrosine kinase [50068] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [50069] (3 PDB entries)

7. C-Crk, N-terminal SH3 domain [50046] (1 species)

   • Species Mouse (Mus musculus) [TaxId:10090] [50047] (3 PDB entries)

8. c-src protein tyrosine kinase [50064] (3 species)

   1. Species Avian sarcoma virus [TaxId:11876] [50067] (2 PDB entries)
      v-src

   2. Species Chicken (Gallus gallus) [TaxId:9031] [50066] (9 PDB entries)

   3. Species Human (Homo sapiens) [TaxId:9606] [50065] (3 PDB entries)

9. Carboxyl-terminal src kinase (csk) [74654] (2 species)

   1. Species Human (Homo sapiens) [TaxId:9606] [74658] (2 PDB entries)

   2. Species Mouse (Mus musculus) [TaxId:10090] [74655] (1 PDB entry)

10. EPS8 SH3 domain [50082] (1 species)

    • Species Mouse (Mus musculus) [TaxId:10090] [50083] (3 PDB entries)

11. Fyn proto-oncogene tyrosine kinase, SH3 domain [50048] (1 species)

    • Species Human (Homo sapiens) [TaxId:9606] [50049] (10 PDB entries)

12. Grb2-related adaptor protein 2 (Mona/Gads) [89293] (1 species)

    • Species Mouse (Mus musculus) [TaxId:10090] [89294] (2 PDB entries)

13. Growth factor receptor-bound protein 2 (GRB2), N- and C-terminal domains [50070] (3 species)

    1. Species Caenorhabditis elegans, SEM-5 [TaxId:6239] [50073] (5 PDB entries)
       Sex muscle abnormal protein 5

    2. Species Human (Homo sapiens) [TaxId:9606] [50071] (6 PDB entries)

    3. Species Mouse (Mus musculus) [TaxId:10090] [50072] (5 PDB entries)

14. Hemapoetic cell kinase Hck [50062] (1 species)

    • Species Human (Homo sapiens) [TaxId:9606] [50063] (6 PDB entries)

15. IL-2 inducible T-cell (Itc) kinase [50060] (1 species)

    • Species Mouse (Mus musculus) [TaxId:10090] [50061] (1 PDB entry)

16. Melanoma inhibitory activity protein [63746] (1 species)

    • Species Human (Homo sapiens) [TaxId:9606] [63747] (3 PDB entries)

17. p47pox (neutrophil cytosolic factor 1) [89295] (1 species)

    • Species Human (Homo sapiens) [TaxId:9606] [89296] (3 PDB entries)

18. p56-lck tyrosine kinase, SH3 domain [50076] (1 species)

    • Species Human (Homo sapiens) [TaxId:9606] [50077] (3 PDB entries)

19. p67phox [74922] (1 species)

    • Species Human (Homo sapiens) [TaxId:9606] [74923] (1 PDB entry)

20. Peroxisomal membrane protein Pex13p [82055] (1 species)

    • Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [82056] (3 PDB entries)

21. Phosphatidylinositol 3-kinase (p85-alpha subunit, pi3k), SH3 domain [50055] (2 species)

    1. Species Cow (Bos taurus) [TaxId:9913] [50057] (2 PDB entries)

    2. Species Human (Homo sapiens) [TaxId:9606] [50056] (3 PDB entries)

22. Phospholipase C, SH3 domain [50074] (1 species)

    • Species Human (Homo sapiens) [TaxId:9606] [50075] (2 PDB entries)

23. Psd-95 [69248] (1 species)
    associates with a guanylate kinase domain

    • Species Rat (Rattus norvegicus) [TaxId:10116] [69249] (3 PDB entries)

24. SH3 domain from nebulin [50050] (1 species)

    • Species Human (Homo sapiens) [TaxId:9606] [50051] (2 PDB entries)

25. tyrosine kinase tec [69246] (1 species)

    • Species Mouse (Mus musculus) [TaxId:10090] [69247] (1 PDB entry)

26. Vav N-terminal SH3 domain [63744] (1 species)

    • Species Mouse (Mus musculus) [TaxId:10090] [63745] (3 PDB entries)

More info for Family b.34.2.1: SH3-domain

Timeline for Family b.34.2.1: SH3-domain:

• Family b.34.2.1: SH3-domain first appeared (with stable ids) in SCOP 1.55
  
• Family b.34.2.1: SH3-domain appears in SCOP 1.63
  
• Family b.34.2.1: SH3-domain appears in SCOP 1.67
  
• Family b.34.2.1: SH3-domain appears in the current release, SCOPe 2.08