SCOPe Funding Alert: SCOPe support from the NIH ended in April 2016. John-Marc Chandonia is the primary maintainer and has continued to develop SCOPe using vacation time. Three proposals to the NIH for continued funding have been unsuccessful. If our current NIH proposal is not funded, SCOPe will shut down permanently in Summer 2017 as Dr. Chandonia will need to seek a new position.

Lineage for Family b.23.1.1: Spermadhesin, CUB domain

  1. Root: SCOPe 2.06
  2. 2017114Class b: All beta proteins [48724] (177 folds)
  3. 2041738Fold b.23: CUB-like [49853] (3 superfamilies)
    sandwich, 10 strands in 2 sheets; jelly-roll
  4. 2041739Superfamily b.23.1: Spermadhesin, CUB domain [49854] (2 families) (S)
    automatically mapped to Pfam PF00431
  5. 2041740Family b.23.1.1: Spermadhesin, CUB domain [49855] (6 protein domains)

Protein Domains:

  1. 2041741Acidic seminal fluid protein (ASFP) [49856] (1 species)
  2. 2041744Complement C1S component [89258] (1 species)
  3. 2041758Major seminal plasma glycoprotein PSP-I [49858] (1 species)
  4. 2041761Major seminal plasma glycoprotein PSP-II [49860] (1 species)
  5. 2041764Mannose-binding protein associated serine protease 2, MASP2 [89256] (2 species)
    duplication: contains two CUB domains separated by an EGF-like domain
    1. 2041765Species Human (Homo sapiens) [TaxId:9606] [110137] (2 PDB entries)
      Uniprot O00187 17-181
    2. 2041769Species Norway rat (Rattus norvegicus) [TaxId:10116] [89257] (1 PDB entry)
  6. 2285141automated matches [328442] (1 species)
    not a true protein

More info for Family b.23.1.1: Spermadhesin, CUB domain

Timeline for Family b.23.1.1: Spermadhesin, CUB domain: