SCOP 1.73: Family b.22.1.1: TNF-like

Lineage for Family b.22.1.1: TNF-like

1. Root: SCOP 1.73

2. Class b: All beta proteins [48724] (165 folds)

3. Fold b.22: TNF-like [49841] (1 superfamily)
   sandwich, 10 strands in 2 sheets; jelly-roll

4. Superfamily b.22.1: TNF-like [49842] (1 family)

5. Family b.22.1.1: TNF-like [49843] (13 proteins)

Proteins:

1. 30 kDa adipocyte complement-related protein [49846] (1 species)

   • Species Mouse (Mus musculus) [TaxId:10090] [49847] (2 PDB entries)

2. A proliferation-inducing ligand, APRIL [117117] (1 species)

   • Species Mouse (Mus musculus) [TaxId:10090] [117118] (5 PDB entries)

3. Apoptosis-2 ligand, apo2l/TRAIL [49851] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [49852] (5 PDB entries)

4. Collagen NC1 trimerisation domain [69230] (2 species)

   1. Species Human (Homo sapiens), isoform X [TaxId:9606] [69231] (1 PDB entry)

   2. Species Mouse (Mus musculus), isoform VIII [TaxId:10090] [101612] (1 PDB entry)

5. Complement c1q globular head, A chain [101613] (1 species)
   hetrotrimer of A, B and C chains

   • Species Human (Homo sapiens) [TaxId:9606] [101614] (1 PDB entry)

6. Complement c1q globular head, B chain [101615] (1 species)
   hetrotrimer of A, B and C chains

   • Species Human (Homo sapiens) [TaxId:9606] [101616] (1 PDB entry)

7. Complement c1q globular head, C chain [101617] (1 species)
   hetrotrimer of A, B and C chains

   • Species Human (Homo sapiens) [TaxId:9606] [101618] (1 PDB entry)

8. Ectodysplasin A, Eda-a1 [101610] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [101611] (2 PDB entries)

9. Extracellular domain of CD40 ligand [49844] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [49845] (2 PDB entries)

10. Soluble part of TALL-1, sTALL-1 (BAFF) [69228] (1 species)

    • Species Human (Homo sapiens) [TaxId:9606] [69229] (6 PDB entries)
      also includes the PDB entry (1otz) that together with the entry (1p0t) provides the multimeric structure of the complex of this protein with its receptor, BAFF-R. In these entries protein chains are designated by both upper case and lower case letters creating problems with its processing and presentation in SCOP

11. TRANCE/RANKL cytokine [63721] (1 species)

    • Species Mouse (Mus musculus) [TaxId:10090] [63722] (3 PDB entries)

12. Tumor necrosis factor (TNF) [49848] (2 species)

    1. Species Human (Homo sapiens) [TaxId:9606] [49849] (7 PDB entries)

    2. Species Mouse (Mus musculus) [TaxId:10090] [49850] (1 PDB entry)

13. Tumor necrosis factor ligand superfamily member 4, OX40L [141127] (2 species)

    1. Species Human (Homo sapiens) [TaxId:9606] [141128] (1 PDB entry)

    2. Species Mouse (Mus musculus) [TaxId:10090] [141129] (2 PDB entries)

More info for Family b.22.1.1: TNF-like

Timeline for Family b.22.1.1: TNF-like:

• Family b.22.1.1: TNF-like first appeared (with stable ids) in SCOP 1.55
  
• Family b.22.1.1: TNF-like appears in SCOP 1.71
  
• Family b.22.1.1: TNF-like appears in SCOP 1.75
  
• Family b.22.1.1: TNF-like appears in the current release, SCOPe 2.08