SCOPe Funding Alert: SCOPe support from the NIH ended in April 2016. John-Marc Chandonia is the primary maintainer and has continued to develop SCOPe using vacation time. Three proposals to the NIH for continued funding have been unsuccessful. If our current NIH proposal is not funded, SCOPe will shut down permanently in Summer 2017 as Dr. Chandonia will need to seek a new position.

Lineage for Protein: gamma-Crystallin

  1. Root: SCOPe 2.06
  2. 2017114Class b: All beta proteins [48724] (177 folds)
  3. 2038595Fold b.11: gamma-Crystallin-like [49694] (1 superfamily)
    sandwich; 8 strands in 2 sheets; greek-key
    duplication: has internal pseudo twofold symmetry
  4. 2038596Superfamily b.11.1: gamma-Crystallin-like [49695] (7 families) (S)
  5. 2038597Family b.11.1.1: Crystallins/Ca-binding development proteins [49696] (5 protein domains)
  6. 2038635Protein gamma-Crystallin [49697] (9 species)
    duplication consists of two domains of this fold

Species:

  1. 2038636Cow (Bos taurus), isoform E [TaxId:9913] [101571] (1 PDB entry)
  2. 2038639Cow (Bos taurus), isoform F [TaxId:9913] [49701] (1 PDB entry)
  3. 2038642Cow (Bos taurus), isoform II (B) [TaxId:9913] [49698] (6 PDB entries)
    1. Domains for 1amm:
      1. 2038643Domain d1amma1: 1amm A:1-85 [23587]
      2. 2038644Domain d1amma2: 1amm A:86-174 [23588]
    2. Domain for 1dsl:
    3. Domains for 1gam:
      1. 2038652Domain d1gama_: 1gam A: [23594]
        C-terminal domain only
      2. 2038653Domain d1gamb_: 1gam B: [23595]
        C-terminal domain only
    4. Domains for 1gcs:
      1. 2038648Domain d1gcsa1: 1gcs A:1-85 [23592]
      2. 2038649Domain d1gcsa2: 1gcs A:86-174 [23593]
    5. Domains for 1i5i:
      1. 2038650Domain d1i5ia1: 1i5i A:1-85 [61786]
        mutant
      2. 2038651Domain d1i5ia2: 1i5i A:86-173 [61787]
        mutant
    6. Domains for 4gcr:
      1. 2038645Domain d4gcra1: 4gcr A:1-85 [23589]
      2. 2038646Domain d4gcra2: 4gcr A:86-174 [23590]
  4. 2038654Cow (Bos taurus), isoform IIIb (D) [TaxId:9913] [49699] (1 PDB entry)
  5. 2038659Cow (Bos taurus), isoform S [TaxId:9913] [49700] (1 PDB entry)
  6. 2038662Human (Homo sapiens) [TaxId:9606] [69202] (1 PDB entry)
  7. 2038665Human (Homo sapiens), isoform D [TaxId:9606] [89230] (2 PDB entries)
    1. Domains for 1h4a:
      1. 2038666Domain d1h4ax1: 1h4a X:1-85 [83479]
        mutant
      2. 2038667Domain d1h4ax2: 1h4a X:87-174 [83480]
        mutant
    2. Domains for 1hk0:
      1. 2038668Domain d1hk0x1: 1hk0 X:1-85 [83522]
      2. 2038669Domain d1hk0x2: 1hk0 X:87-174 [83523]
  8. 2038670Mouse (Mus musculus) [TaxId:10090] [255018] (3 PDB entries)
    1. Domains for 1zwm:
      1. 2038671Domain d1zwma1: 1zwm A:1-90 [241171]
        automated match to d1amma1
      2. 2038672Domain d1zwma2: 1zwm A:91-177 [241172]
        automated match to d1amma2
    2. Domains for 1zwo:
      1. 2038673Domain d1zwoa1: 1zwo A:1-90 [241173]
        automated match to d1amma1
      2. 2038674Domain d1zwoa2: 1zwo A:91-177 [241174]
        automated match to d1amma2
    3. Domains for 2a5m:
      1. 2038675Domain d2a5ma1: 2a5m A:1-90 [241212]
        automated match to d1amma1
      2. 2038676Domain d2a5ma2: 2a5m A:91-177 [241213]
        automated match to d1amma2
  9. 2288134Gallus gallus [TaxId:9031] [331435] (2 PDB entries)
    1. Domains for 5v14:
      1. 2288135Domain d5v14a1: 5v14 A:1-90 [331436]
        automated match to d1zwma1
      2. 2288136Domain d5v14a2: 5v14 A:91-177 [331437]
        automated match to d1zwma2
    2. Domains for 5vh1:
      1. 2291363Domain d5vh1a1: 5vh1 A:1-90 [334664]
        automated match to d1zwma1
      2. 2291364Domain d5vh1a2: 5vh1 A:91-177 [334665]
        automated match to d1zwma2

More info for Protein gamma-Crystallin from b.11.1.1: Crystallins/Ca-binding development proteins

Timeline for Protein gamma-Crystallin from b.11.1.1: Crystallins/Ca-binding development proteins: