SCOPe Funding Alert: SCOPe support from the NIH ended in April 2016. John-Marc Chandonia is the primary maintainer and has continued to develop SCOPe using vacation time. Three proposals to the NIH for continued funding have been unsuccessful. If our current NIH proposal is not funded, SCOPe will shut down permanently in Summer 2017 as Dr. Chandonia will need to seek a new position.

Lineage for Family b.11.1.1: Crystallins/Ca-binding development proteins

  1. Root: SCOPe 2.06
  2. 2017114Class b: All beta proteins [48724] (177 folds)
  3. 2038595Fold b.11: gamma-Crystallin-like [49694] (1 superfamily)
    sandwich; 8 strands in 2 sheets; greek-key
    duplication: has internal pseudo twofold symmetry
  4. 2038596Superfamily b.11.1: gamma-Crystallin-like [49695] (7 families) (S)
  5. 2038597Family b.11.1.1: Crystallins/Ca-binding development proteins [49696] (5 protein domains)

Protein Domains:

  1. 2038598beta-Crystallin [49702] (4 species)
    duplication consists of two domains of this fold
    1. 2038599Species Cow (Bos taurus) [TaxId:9913] [49703] (2 PDB entries)
    2. 2038610Species Human (Homo sapiens) [TaxId:9606] [101572] (2 PDB entries)
    3. 2038617Species Mouse (Mus musculus) [TaxId:10090] [49705] (1 PDB entry)
    4. 2038620Species Norway rat (Rattus norvegicus), isoform E [TaxId:10116] [49704] (6 PDB entries)
  2. 2038635gamma-Crystallin [49697] (9 species)
    duplication consists of two domains of this fold
    1. 2038636Species Cow (Bos taurus), isoform E [TaxId:9913] [101571] (1 PDB entry)
    2. 2038639Species Cow (Bos taurus), isoform F [TaxId:9913] [49701] (1 PDB entry)
    3. 2038642Species Cow (Bos taurus), isoform II (B) [TaxId:9913] [49698] (6 PDB entries)
    4. 2038654Species Cow (Bos taurus), isoform IIIb (D) [TaxId:9913] [49699] (1 PDB entry)
    5. 2038659Species Cow (Bos taurus), isoform S [TaxId:9913] [49700] (1 PDB entry)
    6. 2038662Species Human (Homo sapiens) [TaxId:9606] [69202] (1 PDB entry)
    7. 2038665Species Human (Homo sapiens), isoform D [TaxId:9606] [89230] (2 PDB entries)
    8. 2038670Species Mouse (Mus musculus) [TaxId:10090] [255018] (3 PDB entries)
    9. 2288134Species Gallus gallus [TaxId:9031] [331435] (1 PDB entry)
  3. 2038677Protein S [49706] (1 species)
    duplication consists of two domains of this fold
  4. 2038684Spherulin 3a (S3a) [49708] (1 species)
  5. 2038689automated matches [254533] (1 species)
    not a true protein

More info for Family b.11.1.1: Crystallins/Ca-binding development proteins

Timeline for Family b.11.1.1: Crystallins/Ca-binding development proteins: