SCOPe Funding Alert: SCOPe support from the NIH ended in April 2016. John-Marc Chandonia is the primary maintainer and has continued to develop SCOPe using vacation time. Three proposals to the NIH for continued funding have been unsuccessful. If our current NIH proposal is not funded, SCOPe will shut down permanently in Summer 2017 as Dr. Chandonia will need to seek a new position.

Lineage for Protein: Synaptogamin I

  1. Root: SCOPe 2.06
  2. 2017114Class b: All beta proteins [48724] (177 folds)
  3. 2038038Fold b.7: C2 domain-like [49561] (5 superfamilies)
    sandwich; 8 strands in 2 sheets; greek-key
  4. 2038039Superfamily b.7.1: C2 domain (Calcium/lipid-binding domain, CaLB) [49562] (3 families) (S)
    two constituent families are related by circular permutation
  5. 2038183Family b.7.1.2: Synaptotagmin-like (S variant) [49575] (11 protein domains)
    topologically similar to the C-terminal domain of PapD
  6. 2038208Protein Synaptogamin I [49576] (3 species)
    duplication: contains tandem repeat of two similar domains

Species:

  1. 2038209Human (Homo sapiens) [TaxId:9606] [158946] (10 PDB entries)
    1. Domain for 2k45:
    2. Domain for 2k4a:
    3. Domains for 2k8m:
      1. 2038218Domain d2k8ma1: 2k8m A:3-128 [242415]
        Other proteins in same PDB: d2k8ma2, d2k8mb_, d2k8mc_, d2k8md2
        automated match to d1byna_
      2. 2038219Domain d2k8md1: 2k8m D:3-128 [242418]
        Other proteins in same PDB: d2k8ma2, d2k8mb_, d2k8mc_, d2k8md2
        automated match to d1byna_
    4. Domains for 2ki6:
      1. 2038222Domain d2ki6a_: 2ki6 A: [242524]
        Other proteins in same PDB: d2ki6b_, d2ki6c_, d2ki6d_, d2ki6e_
        automated match to d1byna_
      2. 2038223Domain d2ki6f_: 2ki6 F: [242529]
        Other proteins in same PDB: d2ki6b_, d2ki6c_, d2ki6d_, d2ki6e_
        automated match to d1byna_
    5. Domain for 2lha:
    6. Domains for 2r83:
      1. 2038214Domain d2r83a1: 2r83 A:268-418 [151670]
        automated match to d1dqva2
        complexed with cl
      2. 2038215Domain d2r83a2: 2r83 A:140-267 [238850]
        automated match to d1dqva1
        complexed with cl
      3. 2038216Domain d2r83b1: 2r83 B:268-418 [151671]
        automated match to d1dqva2
        complexed with cl
      4. 2038217Domain d2r83b2: 2r83 B:140-267 [238851]
        automated match to d1dqva1
        complexed with cl
    7. Domain for 3f00:
    8. Domain for 3f01:
    9. Domain for 3f04:
    10. Domain for 3f05:
  2. 2038225Norway rat (Rattus norvegicus) [TaxId:10116] [49577] (7 PDB entries)
    Uniprot P21707 271-419 ! Uniprot P21707 271-419
    1. Domain for 1byn:
    2. Domain for 1k5w:
    3. Domain for 1rsy:
    4. Domain for 1tjm:
    5. Domain for 1tjx:
    6. Domain for 1uov:
    7. Domain for 1uow:
  3. 2292135Mus musculus [TaxId:10090] [335436] (1 PDB entry)

More info for Protein Synaptogamin I from b.7.1.2: Synaptotagmin-like (S variant)

Timeline for Protein Synaptogamin I from b.7.1.2: Synaptotagmin-like (S variant):