SCOPe 2.03: Family b.7.1.1: PLC-like (P variant)

Lineage for Family b.7.1.1: PLC-like (P variant)

1. Root: SCOPe 2.03

2. Class b: All beta proteins [48724] (174 folds)

3. Fold b.7: C2 domain-like [49561] (5 superfamilies)
   sandwich; 8 strands in 2 sheets; greek-key

4. Superfamily b.7.1: C2 domain (Calcium/lipid-binding domain, CaLB) [49562] (3 families)
   two constituent families are related by circular permutation

5. Family b.7.1.1: PLC-like (P variant) [49563] (12 proteins)

Proteins:

1. Domain from cytosolic phospholipase A2 [49566] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [49567] (3 PDB entries)

2. Domain from protein kinase C delta [49573] (1 species)
   rudiment form lacking calcium-binding site

   • Species Norway rat (Rattus norvegicus) [TaxId:10116] [49574] (1 PDB entry)

3. Domain from protein kinase C epsilon [69196] (1 species)
   Calcium-independent

   • Species Rat (Rattus rattus) [TaxId:10117] [69197] (1 PDB entry)

4. E3 ubiquitin-protein ligase Itchy [141103] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [141104] (1 PDB entry)
     Uniprot Q96J02 13-145

5. Fantom [158942] (1 species)
   RPGR-interacting protein 1-like protein

   • Species Human (Homo sapiens) [TaxId:9606] [158943] (1 PDB entry)
     Uniprot Q68CZ1 596-737

6. Multiple C2 and transmembrane domain-containing protein 2, MCTP2 [158940] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [158941] (1 PDB entry)
     Uniprot Q6DN12 504-629

7. Phoshoinositide 3-kinase (PI3K) [49570] (2 species)

   1. Species Human (Homo sapiens) [TaxId:9606] [49572] (19 PDB entries)

   2. Species Pig (Sus scrofa) [TaxId:9823] [49571] (5 PDB entries)

8. Phospholipase C-beta-2 [158944] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [158945] (2 PDB entries)
     Uniprot Q00722 678-799

9. PI-specific phospholipase C isozyme D1 (PLC-D1), C-terminal domain [49564] (1 species)

   • Species Norway rat (Rattus norvegicus) [TaxId:10116] [49565] (10 PDB entries)

10. Pten tumor suppressor (Phoshphoinositide phosphatase), C-terminal domain [49568] (1 species)

    • Species Human (Homo sapiens) [TaxId:9606] [49569] (1 PDB entry)

11. Unc-13 homolog A [141105] (1 species)

    • Species Norway rat (Rattus norvegicus) [TaxId:10116] [141106] (2 PDB entries)
      Uniprot Q62768 1-128! Uniprot Q62768 2-150

12. automated matches [190564] (2 species)
    not a true protein

    1. Species Human (Homo sapiens) [TaxId:9606] [188151] (1 PDB entry)

    2. Species Norway rat (Rattus norvegicus) [TaxId:10116] [187552] (2 PDB entries)

More info for Family b.7.1.1: PLC-like (P variant)

Timeline for Family b.7.1.1: PLC-like (P variant):

• Family b.7.1.1: PLC-like (P variant) first appeared (with stable ids) in SCOP 1.55
  
• Family b.7.1.1: PLC-like (P variant) appears in SCOPe 2.02
  
• Family b.7.1.1: PLC-like (P variant) appears in SCOPe 2.04
  
• Family b.7.1.1: PLC-like (P variant) appears in the current release, SCOPe 2.08