SCOPe Funding Alert: SCOPe support from the NIH ended in April 2016. John-Marc Chandonia is the primary maintainer and has continued to develop SCOPe using vacation time. Three proposals to the NIH for continued funding have been unsuccessful. If our current NIH proposal is not funded, SCOPe will shut down permanently in Summer 2017 as Dr. Chandonia will need to seek a new position.

Lineage for Family b.1.6.1: Cadherin

  1. Root: SCOPe 2.06
  2. 2017114Class b: All beta proteins [48724] (177 folds)
  3. 2017115Fold b.1: Immunoglobulin-like beta-sandwich [48725] (33 superfamilies)
    sandwich; 7 strands in 2 sheets; greek-key
    some members of the fold have additional strands
  4. 2030835Superfamily b.1.6: Cadherin-like [49313] (3 families) (S)
  5. 2030836Family b.1.6.1: Cadherin [49314] (4 protein domains)

Protein Domains:

  1. 2030837C-cadherin ectodomain [74851] (1 species)
    five-domain fragment
  2. 2030844E-cadherin (epithelial) [49317] (2 species)
    synonym: uvomorulin
    1. 2030845Species Human (Homo sapiens) [TaxId:9606] [81981] (12 PDB entries)
    2. 2030859Species Mouse (Mus musculus) [TaxId:10090] [49318] (14 PDB entries)
  3. 2030906N-cadherin (neural) [49315] (1 species)
  4. 2284341automated matches [327642] (1 species)
    not a true protein

More info for Family b.1.6.1: Cadherin

Timeline for Family b.1.6.1: Cadherin: