Lineage for Family b.1.2.1: Fibronectin type III

  1. Root: SCOP 1.71
  2. 546417Class b: All beta proteins [48724] (149 folds)
  3. 546418Fold b.1: Immunoglobulin-like beta-sandwich [48725] (25 superfamilies)
    sandwich; 7 strands in 2 sheets; greek-key
    some members of the fold have additional strands
  4. 550820Superfamily b.1.2: Fibronectin type III [49265] (1 family) (S)
  5. 550821Family b.1.2.1: Fibronectin type III [49266] (28 proteins)
    Pfam 00041

Proteins:

  1. 550822Ciliary neurotrophic factor receptor alpha [110060] (1 species)
  2. 550825Common beta-chain in the GM-CSF, IL-3 and IL-5 receptors [49289] (1 species)
    duplication: consists of four similar domains; dimerizes by swapping the C-terminal strands of domains 1 and 3
  3. 550837Contactin 3 (KIAA1496) [117055] (1 species)
  4. 550840Cytokine receptor gp130 cytokine-binding domains [49295] (1 species)
  5. 550857Erythropoietin (EPO) receptor [49282] (1 species)
  6. 550879Extracellular region of human tissue factor [49267] (2 species)
    tandem of fibronectin type III domains
    1. 550880Species Human (Homo sapiens) [TaxId:9606] [49268] (10 PDB entries)
    2. 550905Species Rabbit (Oryctolagus cuniculus) [TaxId:9986] [49269] (1 PDB entry)
  7. 550910Fibronectin type 3 and ankyrin repeat domains 1 protein, FANK1 [117053] (1 species)
  8. 550913Fibronectin type III domain from chitinase A1. [81975] (1 species)
  9. 550916Fibronectin type-III domain containing protein 3a, FNDC3A (KIAA0970) [117057] (1 species)
  10. 550919Fibronectin, different Fn3 modules [49270] (2 species)
    1. 550920Species Human (Homo sapiens) [TaxId:9606] [49271] (9 PDB entries)
    2. 550935Species Mouse (Mus musculus) [TaxId:10090] [49272] (2 PDB entries)
  11. 550940Granulocyte colony-stimulating factor (GC-SF) receptor [49291] (1 species)
  12. 550956Growth hormone receptor [49280] (1 species)
  13. 550980Host cell factor 2, HCF-2 [117051] (1 species)
  14. 550983Integrin beta-4 subunit [49278] (1 species)
  15. 550989Interferon-alpha/beta receptor beta chain [89199] (1 species)
  16. 550995Interferon-gamma receptor alpha chain [49293] (1 species)
  17. 551008Interleukin-10 receptor 1, IL-10R1 [63670] (1 species)
  18. 551016Interleukin-4 receptor alpha chain [49287] (1 species)
  19. 551020Interleukin-6 receptor alpha chain, domains 2 and 3 [81977] (1 species)
  20. 551026KIAA0343 protein [101531] (1 species)
  21. 551030KIAA1355 [110058] (1 species)
  22. 551033KIAA1568 protein [101529] (1 species)
  23. 551037Neural cell adhesion molecule 1, NCAM [89197] (1 species)
  24. 551040Neuroglian, two amino proximal Fn3 repeats [49276] (1 species)
    tandem of fibronectin type III domains
  25. 551044Prolactin receptor [49284] (2 species)
    1. 551045Species Human (Homo sapiens) [TaxId:9606] [49285] (1 PDB entry)
    2. 551048Species Rat (Rattus norvegicus) [TaxId:10116] [49286] (1 PDB entry)
  26. 551053Tenascin [49273] (3 species)
    1. 551054Species Chicken (Gallus gallus) [TaxId:9031] [49274] (1 PDB entry)
    2. 551059Species Human (Homo sapiens) [TaxId:9606] [49275] (1 PDB entry)
    3. 551061Species Rat (Rattus norvegicus) [TaxId:10116] [110057] (1 PDB entry)
  27. 551065The p40 domain of interleukin-12 (IL-12 beta chain), domains 2 and 3 [63672] (1 species)
  28. 551071Type I titin module [49297] (1 species)

More info for Family b.1.2.1: Fibronectin type III

Timeline for Family b.1.2.1: Fibronectin type III: