Lineage for Family a.133.1.2: Vertebrate phospholipase A2

  1. Root: SCOP 1.65
  2. 275720Class a: All alpha proteins [46456] (179 folds)
  3. 286043Fold a.133: Phospholipase A2, PLA2 [48618] (1 superfamily)
    common core: 2 helices, disulphide-linked, and a calcium-binding loop
  4. 286044Superfamily a.133.1: Phospholipase A2, PLA2 [48619] (3 families) (S)
  5. 286049Family a.133.1.2: Vertebrate phospholipase A2 [48623] (2 proteins)

Proteins:

  1. 286050Phospholipase A2 [48637] (4 species)
    1. 286051Species Cow (Bos taurus), pancreas [TaxId:9913] [48639] (22 PDB entries)
    2. 286074Species Human (Homo sapiens), SPLA2 [TaxId:9606] [74797] (2 PDB entries)
      group X secretory phospholipase A2
    3. 286080Species Human (Homo sapiens), synovial fluid [TaxId:9606] [48638] (9 PDB entries)
    4. 286102Species Pig (Sus scrofa), pancreas [TaxId:9823] [48640] (13 PDB entries)
  2. 286123Snake phospholipase A2 [48624] (27 species)
    1. 286124Species Bothrops godmani [48645] (1 PDB entry)
      Monomeric Lys-49 phospholipase A2 homologue
    2. 286126Species Bothrops pirajai, Piratoxin-II (PRTX-II) [TaxId:113192] [48633] (1 PDB entry)
    3. 286129Species Chinese water moccasin (Agkistrodon halys pallas), different isoforms [48628] (9 PDB entries)
    4. 286158Species Eastern cottonmouth snake (Agkistridon piscivorus) [48629] (2 PDB entries)
    5. 286162Species Hundred-pace snake (Agkistrodon acutus) [TaxId:36307] [74796] (2 PDB entries)
      monomeric Lys-49 phospholipase A2 homologue
    6. 286165Species Indian cobra (Naja naja naja) [48626] (3 PDB entries)
    7. 286173Species Indian cobra (Naja naja sagittifera), acidic isoform 1 [TaxId:195058] [89168] (1 PDB entry)
    8. 286175Species Indian cobra (Naja naja sagittifera), calcium-free isoform 5 [TaxId:195058] [89172] (2 PDB entries)
    9. 286178Species Indian cobra (Naja naja sagittifera), isoform 2 [TaxId:195058] [89169] (2 PDB entries)
    10. 286181Species Indian cobra (Naja naja sagittifera), isoform 3 [TaxId:195058] [89170] (2 PDB entries)
    11. 286184Species Indian cobra (Naja naja sagittifera), isoform 4 [TaxId:195058] [89171] (1 PDB entry)
    12. 286186Species Indian cobra (Naja naja), a C49 isoform 2 [TaxId:35670] [89166] (1 PDB entry)
    13. 286188Species Indian cobra (Naja naja), isoform 3 [TaxId:35670] [89167] (1 PDB entry)
    14. 286190Species Indian krait (Bungarus caeruleus), different isoforms [TaxId:132961] [48636] (4 PDB entries)
    15. 286198Species King cobra (Ophiophagus hannah) [TaxId:8665] [81939] (1 PDB entry)
    16. 286202Species Mainland tiger snake (Notechis scutatus scutatus), notechis II-5 [TaxId:8663] [48632] (1 PDB entry)
      neurotoxic phospholipase a2
    17. 286205Species Mainland tiger snake (Notechis scutatus scutatus), notexin [TaxId:8663] [48631] (1 PDB entry)
      presynaptic neurotoxic phospholipase A2
    18. 286207Species Many-banded krait (Bungarus multicinctus), beta2-bungarotoxin [TaxId:8616] [48642] (1 PDB entry)
    19. 286209Species Russell's viper (Vipera russelli) [TaxId:8707] [48634] (1 PDB entry)
      anticoagulant class II phospholipase A2
    20. 286211Species Sand viper (Vipera ammodytes meridionalis), vipoxin catalytic subunit [TaxId:8704] [88518] (2 PDB entries)
    21. 286214Species Sand viper (Vipera ammodytes meridionalis), vipoxin inhibitor [TaxId:8704] [88517] (3 PDB entries)
    22. 286218Species Snake (Bothrops pirajai), piratoxin III [TaxId:113192] [69123] (1 PDB entry)
      Asp-49 phospholipase A2 homologue
    23. 286221Species Snake (Daboia russelli pulchella) [48630] (7 PDB entries)
    24. 286236Species Taiwan cobra (Naja naja atra) [TaxId:8656] [48625] (2 PDB entries)
    25. 286240Species Terciopelo (Bothrops asper), myotoxin I [TaxId:8722] [48644] (1 PDB entry)
    26. 286243Species Viper (Deinagkistrodon acutus) [TaxId:36307] [69122] (1 PDB entry)
    27. 286246Species Western diamondback rattlesnake (Crotalus atrox) [TaxId:8730] [48627] (1 PDB entry)

More info for Family a.133.1.2: Vertebrate phospholipase A2

Timeline for Family a.133.1.2: Vertebrate phospholipase A2: