Lineage for Species: Human (Homo sapiens) [TaxId: 9606]

  1. Root: SCOP 1.75
  2. 758332Class a: All alpha proteins [46456] (284 folds)
  3. 776482Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
    multihelical; 3 layers or orthogonally packed helices
  4. 776483Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (1 family) (S)
  5. 776484Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (33 proteins)
  6. 776557Protein Estrogen receptor alpha [48519] (1 species)
  7. 776558Species Human (Homo sapiens) [TaxId:9606] [48520] (29 PDB entries)
    Uniprot P03372 307-551

PDB entries in Species: Human (Homo sapiens) [TaxId: 9606]:

  1. Domain(s) for 1a52:
    1. 776592Domain d1a52a_: 1a52 A: [19296]
    2. 776593Domain d1a52b_: 1a52 B: [19297]
      complexed with au, est
  2. Domain(s) for 1ere:
    1. 776599Domain d1erea_: 1ere A: [19300]
    2. 776600Domain d1ereb_: 1ere B: [19301]
    3. 776601Domain d1erec_: 1ere C: [19302]
    4. 776602Domain d1ered_: 1ere D: [19303]
    5. 776603Domain d1eree_: 1ere E: [19304]
    6. 776604Domain d1eref_: 1ere F: [19305]
      complexed with est
  3. Domain(s) for 1err:
    1. 776597Domain d1erra_: 1err A: [19298]
    2. 776598Domain d1errb_: 1err B: [19299]
      complexed with cbm, ral
  4. Domain(s) for 1g50:
    1. 776610Domain d1g50a_: 1g50 A: [65149]
    2. 776611Domain d1g50b_: 1g50 B: [65150]
    3. 776612Domain d1g50c_: 1g50 C: [65151]
      complexed with est
  5. Domain(s) for 1gwq:
    1. 776586Domain d1gwqa_: 1gwq A: [76366]
      complex with raloxifene core and TIF2 NRbox2 peptide; chains C and D
    2. 776587Domain d1gwqb_: 1gwq B: [76367]
      complex with raloxifene core and TIF2 NRbox2 peptide; chains C and D
      complexed with ztw
  6. Domain(s) for 1gwr:
    1. 776588Domain d1gwra_: 1gwr A: [76368]
      complex with 17beta-oestradiol and TIF2 NRbox3 peptide; chains C and D
    2. 776589Domain d1gwrb_: 1gwr B: [76369]
      complex with 17beta-oestradiol and TIF2 NRbox3 peptide; chains C and D
      complexed with est
  7. Domain(s) for 1l2i:
    1. 776560Domain d1l2ia_: 1l2i A: [73503]
    2. 776561Domain d1l2ib_: 1l2i B: [73504]
      complexed with ccs, cl, etc
  8. Domain(s) for 1pcg:
    1. 776590Domain d1pcga_: 1pcg A: [94432]
    2. 776591Domain d1pcgb_: 1pcg B: [94433]
      complexed with est; mutant
  9. Domain(s) for 1qkt:
    • 776579Domain d1qkta_: 1qkt A: [19295]
      complex with estradiol
      complexed with est; mutant
  10. Domain(s) for 1qku:
    1. 776605Domain d1qkua_: 1qku A: [19306]
      complex with estradiol
    2. 776606Domain d1qkub_: 1qku B: [19307]
      complex with estradiol
    3. 776607Domain d1qkuc_: 1qku C: [19308]
      complex with estradiol
      complexed with est
  11. Domain(s) for 1r5k:
    1. 776594Domain d1r5ka_: 1r5k A: [111706]
    2. 776595Domain d1r5kb_: 1r5k B: [111707]
    3. 776596Domain d1r5kc_: 1r5k C: [111708]
      complexed with gw5
  12. Domain(s) for 1sj0:
  13. Domain(s) for 1uom:
  14. Domain(s) for 1xp1:
  15. Domain(s) for 1xp6:
  16. Domain(s) for 1xp9:
  17. Domain(s) for 1xpc:
  18. Domain(s) for 1xqc:
    1. 776581Domain d1xqca1: 1xqc A:307-548 [122233]
      automatically matched to d1qkta_
      complexed with aej; mutant
    2. 776582Domain d1xqcb1: 1xqc B:307-548 [122234]
      automatically matched to d1qkta_
      complexed with aej; mutant
    3. 776583Domain d1xqcc1: 1xqc C:307-548 [122235]
      automatically matched to d1qkta_
      complexed with aej; mutant
    4. 776584Domain d1xqcd1: 1xqc D:307-548 [122236]
      automatically matched to d1qkta_
      complexed with aej; mutant
  19. Domain(s) for 2ayr:
  20. Domain(s) for 2iog:
  21. Domain(s) for 2iok:
    1. 776608Domain d2ioka1: 2iok A:306-544 [147747]
      automatically matched to d1qkua_
      complexed with iok
    2. 776609Domain d2iokb1: 2iok B:1306-1544 [147748]
      automatically matched to d1qkua_
      complexed with iok
  22. Domain(s) for 2ouz:
  23. Domain(s) for 2pog:
  24. Domain(s) for 2q70:
  25. Domain(s) for 2r6w:
    1. 776571Domain d2r6wa1: 2r6w A:306-549 [151621]
      automatically matched to d1qkta_
      complexed with llb; mutant
    2. 776572Domain d2r6wb1: 2r6w B:306-546 [151622]
      automatically matched to d1qkta_
      complexed with llb; mutant
  26. Domain(s) for 2r6y:
    1. 776569Domain d2r6ya1: 2r6y A:306-549 [151623]
      automatically matched to d1qkta_
      complexed with llc; mutant
    2. 776570Domain d2r6yb1: 2r6y B:306-545 [151624]
      automatically matched to d1qkta_
      complexed with llc; mutant
  27. Domain(s) for 3dt3:
    1. 776577Domain d3dt3a1: 3dt3 A:306-550 [157848]
      automatically matched to d1qkua_
      complexed with 369
    2. 776578Domain d3dt3b1: 3dt3 B:306-548 [157849]
      automatically matched to d1qkua_
      complexed with 369
  28. Domain(s) for 3erd:
    1. 776575Domain d3erda_: 3erd A: [19293]
      complex with diethylstilbestrol and a peptide
    2. 776576Domain d3erdb_: 3erd B: [19294]
      complex with diethylstilbestrol and a peptide
      complexed with cbm, cl, des
  29. Domain(s) for 3ert:
    • 776574Domain d3erta_: 3ert A: [19292]
      complex with 4-hydroxytamoxifen
      complexed with oht

More info for Species Human (Homo sapiens) [TaxId:9606] from a.123.1.1 Estrogen receptor alpha

Timeline for Species Human (Homo sapiens) [TaxId:9606] from a.123.1.1 Estrogen receptor alpha: