Lineage for Species: Human (Homo sapiens)

  1. Root: SCOP 1.63
  2. 208553Class a: All alpha proteins [46456] (171 folds)
  3. 217440Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
    multihelical; 3 layers or orthogonally packed helices
  4. 217441Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (1 family) (S)
  5. 217442Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (20 proteins)
  6. 217450Protein Estrogen receptor alpha [48519] (1 species)
  7. 217451Species Human (Homo sapiens) [TaxId:9606] [48520] (11 PDB entries)

PDB entries in Species: Human (Homo sapiens):

  1. Domain(s) for 1a52:
    1. 217462Domain d1a52a_: 1a52 A: [19296]
    2. 217463Domain d1a52b_: 1a52 B: [19297]
      complexed with au, est
  2. Domain(s) for 1ere:
    1. 217466Domain d1erea_: 1ere A: [19300]
    2. 217467Domain d1ereb_: 1ere B: [19301]
    3. 217468Domain d1erec_: 1ere C: [19302]
    4. 217469Domain d1ered_: 1ere D: [19303]
    5. 217470Domain d1eree_: 1ere E: [19304]
    6. 217471Domain d1eref_: 1ere F: [19305]
      complexed with est
  3. Domain(s) for 1err:
    1. 217464Domain d1erra_: 1err A: [19298]
    2. 217465Domain d1errb_: 1err B: [19299]
      complexed with cbm, ral
  4. Domain(s) for 1g50:
    1. 217472Domain d1g50a_: 1g50 A: [65149]
    2. 217473Domain d1g50b_: 1g50 B: [65150]
    3. 217474Domain d1g50c_: 1g50 C: [65151]
      complexed with est
  5. Domain(s) for 1gwq:
    1. 217458Domain d1gwqa_: 1gwq A: [76366]
    2. 217459Domain d1gwqb_: 1gwq B: [76367]
      complex with raloxifene core and TIF2 NRbox2 peptide; chains C and D
      complexed with ztw
  6. Domain(s) for 1gwr:
    1. 217460Domain d1gwra_: 1gwr A: [76368]
    2. 217461Domain d1gwrb_: 1gwr B: [76369]
      complex with 17beta-oestradiol and TIF2 NRbox3 peptide; chains C and D
      complexed with est
  7. Domain(s) for 1l2i:
    1. 217452Domain d1l2ia_: 1l2i A: [73503]
    2. 217453Domain d1l2ib_: 1l2i B: [73504]
      complexed with ccs, cl, etc
  8. Domain(s) for 1qkt:
    • 217457Domain d1qkta_: 1qkt A: [19295]
      complex with estradiol
      complexed with est; mutant
  9. Domain(s) for 1qku:
    1. 217475Domain d1qkua_: 1qku A: [19306]
    2. 217476Domain d1qkub_: 1qku B: [19307]
    3. 217477Domain d1qkuc_: 1qku C: [19308]
      complex with estradiol
      complexed with est
  10. Domain(s) for 3erd:
    1. 217454Domain d3erda_: 3erd A: [19293]
    2. 217455Domain d3erdb_: 3erd B: [19294]
      complex with diethylstilbestrol and a peptide
      complexed with cbm, cl, des
  11. Domain(s) for 3ert:
    • 217456Domain d3erta_: 3ert A: [19292]
      complex with 4-hydroxytamoxifen
      complexed with oht

More info for Species Human (Homo sapiens) [TaxId:9606] from a.123.1.1 Estrogen receptor alpha

Timeline for Species Human (Homo sapiens) [TaxId:9606] from a.123.1.1 Estrogen receptor alpha: