Lineage for Family a.123.1.1: Nuclear receptor ligand-binding domain

  1. Root: SCOP 1.73
  2. 631650Class a: All alpha proteins [46456] (258 folds)
  3. 647844Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
    multihelical; 3 layers or orthogonally packed helices
  4. 647845Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (1 family) (S)
  5. 647846Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (32 proteins)

Proteins:

  1. 647847Androgen receptor [63621] (3 species)
    1. 647848Species Chimpanzee (Pan troglodytes) [TaxId:9598] [109986] (8 PDB entries)
    2. 647857Species Human (Homo sapiens) [TaxId:9606] [63623] (15 PDB entries)
    3. 647873Species Rat (Rattus norvegicus) [TaxId:10116] [63622] (7 PDB entries)
  2. 647881Bile acid receptor FXR [101433] (2 species)
    1. 647882Species Human (Homo sapiens) [TaxId:9606] [101434] (1 PDB entry)
    2. 647884Species Rat (Rattus norvegicus) [TaxId:10116] [101435] (2 PDB entries)
  3. 647889Ecdysone receptor [101436] (1 species)
  4. 647893Estrogen receptor alpha [48519] (1 species)
  5. 647938Estrogen receptor beta [48521] (2 species)
    1. 647939Species Human (Homo sapiens) [TaxId:9606] [48522] (15 PDB entries)
    2. 647969Species Rat (Rattus norvegicus) [TaxId:10116] [48523] (4 PDB entries)
  6. 647974Glucocorticoid receptor [89140] (1 species)
  7. 647983Hepatocyte nuclear factor 4-alpha [109605] (2 species)
    1. 647984Species Human (Homo sapiens) [TaxId:9606] [109987] (1 PDB entry)
    2. 647986Species Rat (Rattus norvegicus) [TaxId:10116] [89146] (1 PDB entry)
  8. 647991Hepatocyte nuclear factor 4-gamma [81918] (1 species)
  9. 647994Nuclear hormone receptor HR38 [89144] (1 species)
  10. 647998Orphan nuclear receptor ERR3 [81916] (1 species)
  11. 648028Orphan nuclear receptor NR1I3 (CAR) [117014] (2 species)
    1. 648029Species Human (Homo sapiens) [TaxId:9606] [117016] (2 PDB entries)
    2. 648034Species Mouse (Mus musculus) [TaxId:10090] [117015] (2 PDB entries)
  12. 648041Orphan nuclear receptor NR5a2 (LRH-1) [89147] (1 species)
  13. 648045Orphan nuclear receptor NURR1 [89142] (1 species)
  14. 648053Orphan nuclear receptor ROR-alpha [81914] (1 species)
  15. 648057Orphan nuclear receptor ROR-beta [74794] (1 species)
  16. 648062Oxysterols receptor LXR-alpha [109988] (1 species)
  17. 648065Oxysterols receptor LXR-beta [89149] (1 species)
  18. 648083Peroxisome proliferator activated receptor alpha, PPAR-alpha [69109] (1 species)
  19. 648095Peroxisome proliferator activated receptor gamma, PPAR-gamma [48524] (1 species)
  20. 648142Peroxisome proliferator-activated receptor delta, PPAR-DELTA [48526] (1 species)
  21. 648160Pregnane x receptor, PXR [63624] (1 species)
  22. 648168Progesterone receptor [48517] (1 species)
  23. 648182Retinoic acid receptor alpha (RAR-alpha) [48513] (1 species)
  24. 648185Retinoic acid receptor beta (RAR-beta) [117011] (2 species)
    1. 648186Species Human (Homo sapiens) [TaxId:9606] [117013] (1 PDB entry)
    2. 648188Species Mouse (Mus musculus) [TaxId:10090] [117012] (1 PDB entry)
  25. 648191Retinoic acid receptor gamma (RAR-gamma) [48515] (1 species)
  26. 648202Retinoid-X receptor alpha (RXR-alpha) [48510] (2 species)
    1. 648203Species Human (Homo sapiens) [TaxId:9606] [48511] (15 PDB entries)
    2. 648236Species Mouse (Mus musculus) [TaxId:10090] [48512] (2 PDB entries)
  27. 648242Retinoid-X receptor beta (RXR-beta) [74792] (1 species)
  28. 648249Steroid hormone receptor ERR1 [109990] (1 species)
  29. 648252Thyroid hormone receptor alpha1 (TR-alpha1) [48532] (1 species)
  30. 648255Thyroid hormone receptor beta (TR-beta) [48530] (1 species)
  31. 648270Ultraspiracle protein, usp [48534] (2 species)
    the ortholog of RXRs in insects
    1. 648271Species Drosophila melanogaster [TaxId:7227] [48535] (1 PDB entry)
    2. 648278Species Heliothis virescens [TaxId:7102] [63626] (3 PDB entries)
  32. 648282Vitamin D nuclear receptor [48528] (2 species)
    1. 648283Species Human (Homo sapiens) [TaxId:9606] [48529] (11 PDB entries)
    2. 648295Species Rat (Rattus norvegicus) [TaxId:10116] [101432] (6 PDB entries)

More info for Family a.123.1.1: Nuclear receptor ligand-binding domain

Timeline for Family a.123.1.1: Nuclear receptor ligand-binding domain: