Lineage for Fold a.118: alpha-alpha superhelix

  1. Root: SCOPe 2.08
  2. 2685877Class a: All alpha proteins [46456] (290 folds)
  3. 2725421Fold a.118: alpha-alpha superhelix [48370] (28 superfamilies)
    multihelical; 2 (curved) layers: alpha/alpha; right-handed superhelix

Superfamilies:

  1. 2725422a.118.1: ARM repeat [48371] (28 families) (S)
  2. 2726245a.118.3: Sec7 domain [48425] (2 families) (S)
  3. 2726300a.118.4: Lipovitellin-phosvitin complex, superhelical domain [48431] (1 family) (S)
  4. 2726305a.118.5: Bacterial muramidases [48435] (1 family) (S)
  5. 2726312a.118.6: Protein prenylyltransferase [48439] (2 families) (S)
  6. 2726458a.118.7: 14-3-3 protein [48445] (1 family) (S)
    automatically mapped to Pfam PF00244
  7. 2726649a.118.8: TPR-like [48452] (11 families) (S)
  8. 2727055a.118.9: ENTH/VHS domain [48464] (5 families) (S)
  9. 2727193a.118.11: Cytochrome c oxidase subunit E [48479] (2 families) (S)
    automatically mapped to Pfam PF02284
  10. 2727312a.118.12: Ran-GTPase activating protein 1 (RanGAP1), C-terminal domain [69099] (1 family) (S)
    automatically mapped to Pfam PF07834
  11. 2727335a.118.13: Arp2/3 complex 16 kDa subunit ARPC5 [69103] (1 family) (S)
    automatically mapped to Pfam PF04699
  12. 2727358a.118.14: FliG [48029] (2 families) (S)
    fragmented superhelix; consist of 3/4-helical motifs and connecting helices
  13. 2727378a.118.15: Aconitase B, N-terminal domain [74778] (1 family) (S)
    automatically mapped to Pfam PF11791
  14. 2727384a.118.16: Translin [74784] (2 families) (S)
    automatically mapped to Pfam PF01997
  15. 2727431a.118.17: Cullin repeat-like [74788] (3 families) (S)
  16. 2727465a.118.18: HCP-like [81901] (1 family) (S)
  17. 2727473a.118.19: C-terminal domain of Ku80 [101420] (1 family) (S)
    automatically mapped to Pfam PF08785
  18. 2727479a.118.20: Hypothetical protein ST1625 [101424] (1 family) (S)
    automatically mapped to Pfam PF09205
  19. 2727484a.118.21: Chemosensory protein Csp2 [100910] (2 families) (S)
    automatically mapped to Pfam PF03392
  20. 2727502a.118.22: IP3 receptor type 1 binding core, domain 2 [100909] (1 family) (S)
    automatically mapped to Pfam PF01365
  21. 2727507a.118.23: USP8 N-terminal domain-like [140856] (1 family) (S)
  22. 2727513a.118.24: Pseudo ankyrin repeat-like [140860] (1 family) (S)
    contains three helices per turn of the superhelix
  23. 2727519a.118.25: TROVE domain-like [140864] (1 family) (S)
    consist of two superhelical sections arranged like a horse-shoe
    automatically mapped to Pfam PF05731
  24. 2727528a.118.26: MgtE N-terminal domain-like [158791] (2 families) (S)
    made of short helices; approximately 2.5 helices per turn of superhelix
    automatically mapped to Pfam PF03448
  25. 2727550a.118.27: DIL domain-like [310601] (1 family) (S)
    Pfam PF01843
  26. 2727603a.118.28: Proteasome regulatory subunit Rpn2 N-terminal domain-like [345915] (1 family) (S)
  27. 2727612a.118.29: U5 small nuclear riboprotein particle assembly factor Aar2 C-terminal domain-like [345916] (1 family) (S)
    C-terminal part of Pfam PF05282
    Structural similarity with VHS domains (48464) noted in PubMed 21764848, but no compelling evidence of homology
  28. 2727760a.118.30: Pre-mRNA splicing factor Prp38 N-terminal-like [345917] (1 family) (S)
    Pfam PF03371
    Structural similarity to HEAT repeats, according to PubMed 26673105
    Some loops between helices form beta hairpins

More info for Fold a.118: alpha-alpha superhelix

Timeline for Fold a.118: alpha-alpha superhelix: