Lineage for Superfamily a.4.12: TrpR-like

  1. Root: SCOP 1.63
  2. 208553Class a: All alpha proteins [46456] (171 folds)
  3. 210246Fold a.4: DNA/RNA-binding 3-helical bundle [46688] (11 superfamilies)
    core: 3-helices; bundle, closed or partly opened, right-handed twist; up-and down
  4. 211111Superfamily a.4.12: TrpR-like [48295] (2 families) (S)
    contains an extra shared helix after the HTH motif


  1. 211112a.4.12.1: Trp repressor, TrpR [48296] (1 protein)
    intertwined dimer of identical 6-helical subunits
  2. 211137a.4.12.2: Chromosomal replication initiation factor DnaA [81695] (1 protein)
    monomeric; contains additional N-terminal helices

More info for Superfamily a.4.12: TrpR-like

Timeline for Superfamily a.4.12: TrpR-like: