SCOPe 2.08: Superfamily a.4.12: TrpR-like

Lineage for Superfamily a.4.12: TrpR-like

1. Root: SCOPe 2.08

2. Class a: All alpha proteins [46456] (290 folds)

3. Fold a.4: DNA/RNA-binding 3-helical bundle [46688] (14 superfamilies)
   core: 3-helices; bundle, closed or partly opened, right-handed twist; up-and down

4. Superfamily a.4.12: TrpR-like [48295] (4 families)
   contains an extra shared helix after the HTH motif

Families:

1. a.4.12.1: Trp repressor, TrpR [48296] (2 proteins)
   intertwined dimer of identical 6-helical subunits
   automatically mapped to Pfam PF01371

2. a.4.12.2: Chromosomal replication initiation factor DnaA C-terminal domain IV [81695] (1 protein)
   monomeric; contains additional N-terminal helices

3. a.4.12.3: SPO1678-like [158345] (1 protein)
   Pfam PF06627; DUF1153

4. a.4.12.0: automated matches [254246] (1 protein)
   not a true family

More info for Superfamily a.4.12: TrpR-like

Timeline for Superfamily a.4.12: TrpR-like:

• Superfamily a.4.12: TrpR-like first appeared (with stable ids) in SCOP 1.55, called Superfamily a.107.1: Trp repressor
  
• Superfamily a.4.12: TrpR-like appears in SCOPe 2.07