SCOPe 2.06: Family a.102.4.4: Complement components

Lineage for Family a.102.4.4: Complement components

1. Root: SCOPe 2.06

2. Class a: All alpha proteins [46456] (289 folds)

3. Fold a.102: alpha/alpha toroid [48207] (6 superfamilies)
   multihelical; up to seven alpha-hairpins are arranged in closed circular array; there may be sequence similarities between different superfamilies

4. Superfamily a.102.4: Terpenoid cyclases/Protein prenyltransferases [48239] (5 families)

5. Family a.102.4.4: Complement components [48251] (4 proteins)
   probably related to other families, but has no known enzymatic activity

Proteins:

1. C4adg fragment of complement factor C4a [81859] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [81860] (1 PDB entry)

2. Thio-ester containing domain (TED) from Complement C3, aka C3d or C3dg [48252] (2 species)

   1. Species Human (Homo sapiens) [TaxId:9606] [48253] (17 PDB entries)

   2. Species Norway rat (Rattus norvegicus) [TaxId:10116] [48254] (2 PDB entries)

3. Thio-ester containing domain (TED) from Complement C5 [254373] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [254806] (1 PDB entry)

4. automated matches [190371] (1 species)
   not a true protein

   • Species Human (Homo sapiens) [TaxId:9606] [187209] (1 PDB entry)

More info for Family a.102.4.4: Complement components

Timeline for Family a.102.4.4: Complement components:

• Family a.102.4.4: Complement components first appeared (with stable ids) in SCOP 1.55, called Family a.102.4.4: C3D, a C3 fragment and ligand for complement receptor 2
  
• Family a.102.4.4: Complement components appears in SCOPe 2.05
  
• Family a.102.4.4: Complement components appears in SCOPe 2.07
  
• Family a.102.4.4: Complement components appears in the current release, SCOPe 2.08