SCOP 1.75: Family a.60.8.1: HRDC domain from helicases

Lineage for Family a.60.8.1: HRDC domain from helicases

1. Root: SCOP 1.75

2. Class a: All alpha proteins [46456] (284 folds)

3. Fold a.60: SAM domain-like [47768] (16 superfamilies)
   4-5 helices; bundle of two orthogonally packed alpha-hairpins; involved in the interactions with DNA and proteins

4. Superfamily a.60.8: HRDC-like [47819] (4 families)

5. Family a.60.8.1: HRDC domain from helicases [47820] (2 proteins)

Proteins:

1. HRDC domain from RecQ helicase [47821] (2 species)

   1. Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [47822] (1 PDB entry)

   2. Species Escherichia coli [TaxId:562] [140639] (1 PDB entry)
      Uniprot P15043 530-606

2. Werner syndrome ATP-dependent helicase, WRN [140640] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [140641] (3 PDB entries)
     Uniprot Q14191 1140-1239! Uniprot Q14191 1142-1235

More info for Family a.60.8.1: HRDC domain from helicases

Timeline for Family a.60.8.1: HRDC domain from helicases:

• Family a.60.8.1: HRDC domain from helicases first appeared (with stable ids) in SCOP 1.55, called Family a.60.8.1: HRDC domain from RecQ helicase
  
• Family a.60.8.1: HRDC domain from helicases appears in SCOP 1.73
  
• Family a.60.8.1: HRDC domain from helicases appears in SCOPe 2.01
  
• Family a.60.8.1: HRDC domain from helicases appears in the current release, SCOPe 2.08