Lineage for Superfamily a.60.2: RuvA domain 2-like

  1. Root: SCOPe 2.04
  2. 1473060Class a: All alpha proteins [46456] (285 folds)
  3. 1493397Fold a.60: SAM domain-like [47768] (16 superfamilies)
    4-5 helices; bundle of two orthogonally packed alpha-hairpins; involved in the interactions with DNA and proteins
  4. 1493577Superfamily a.60.2: RuvA domain 2-like [47781] (7 families) (S)
    duplication: contains two helix-hairpin-helix (HhH) motifs


  1. 1493578a.60.2.1: DNA helicase RuvA subunit, middle domain [47782] (1 protein)
  2. 1493602a.60.2.2: NAD+-dependent DNA ligase, domain 3 [47786] (1 protein)
  3. 1493609a.60.2.3: Excinuclease UvrC C-terminal domain [81795] (1 protein)
  4. 1493613a.60.2.4: Topoisomerase V repeat domain [140626] (1 protein)
    this is a repeat family; one repeat unit is 2csb A:351-409 found in domain
  5. 1493632a.60.2.5: Hef domain-like [140629] (4 proteins)
    helicase/nuclease domain; forms homo and heterodimers; probably includes the Excinuclease UvrC C-terminal domain ((81795), that contains a single NMR structure of a monomeric truncated domain, 1kft)
  6. 1493658a.60.2.6: Tex HhH-containing domain-like [158531] (1 protein)
    tandem repeat of two Ruva_2-like domains
  7. 1493667a.60.2.7: ComEA-like [158534] (2 proteins)
    sequence similarity to the HhH-motif domains of the PsbU-like and Tex-like families

More info for Superfamily a.60.2: RuvA domain 2-like

Timeline for Superfamily a.60.2: RuvA domain 2-like: