Lineage for Fold a.60: SAM domain-like

  1. Root: SCOPe 2.07
  2. 2299346Class a: All alpha proteins [46456] (289 folds)
  3. 2328564Fold a.60: SAM domain-like [47768] (16 superfamilies)
    4-5 helices; bundle of two orthogonally packed alpha-hairpins; involved in the interactions with DNA and proteins

Superfamilies:

  1. 2328565a.60.1: SAM/Pointed domain [47769] (4 families) (S)
  2. 2328799a.60.2: RuvA domain 2-like [47781] (7 families) (S)
    duplication: contains two helix-hairpin-helix (HhH) motifs
  3. 2328899a.60.3: C-terminal domain of RNA polymerase alpha subunit [47789] (1 family) (S)
    contains one classic and one pseudo HhH motifs
  4. 2328929a.60.4: Rad51 N-terminal domain-like [47794] (4 families) (S)
    contains one classic and one pseudo HhH motifs
  5. 2328987a.60.5: Barrier-to-autointegration factor, BAF [47798] (1 family) (S)
    contains one classic and one pseudo HhH motifs
    automatically mapped to Pfam PF02961
  6. 2329042a.60.6: DNA polymerase beta, N-terminal domain-like [47802] (2 families) (S)
    contains one classic and one pseudo HhH motifs
  7. 2329325a.60.7: 5' to 3' exonuclease, C-terminal subdomain [47807] (2 families) (S)
  8. 2329380a.60.8: HRDC-like [47819] (5 families) (S)
  9. 2329429a.60.9: lambda integrase-like, N-terminal domain [47823] (2 families) (S)
  10. 2329505a.60.10: Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain [47831] (1 family) (S)
  11. 2329521a.60.11: Hypothetical protein YjbJ [69047] (2 families) (S)
    automatically mapped to Pfam PF05532
  12. 2329531a.60.12: PsbU/PolX domain-like [81585] (3 families) (S)
    contains one classic and one pseudo HhH motifs
  13. 2329866a.60.13: Putative methyltransferase TM0872, insert domain [81799] (1 family) (S)
  14. 2329877a.60.14: eIF2alpha middle domain-like [116742] (2 families) (S)
  15. 2329899a.60.15: YozE-like [140652] (1 family) (S)
  16. 2329908a.60.16: GspK insert domain-like [158544] (1 family) (S)
    tandem repeat of two SAM-like domains iserted into pilin fold; domain 1 contains one classic HhH motif

More info for Fold a.60: SAM domain-like

Timeline for Fold a.60: SAM domain-like: