Lineage for Family a.45.1.1: Glutathione S-transferase (GST), C-terminal domain

  1. Root: SCOP 1.69
  2. 436025Class a: All alpha proteins [46456] (218 folds)
  3. 443394Fold a.45: Glutathione S-transferase (GST), C-terminal domain [47615] (1 superfamily)
    core: 4 helices; bundle, closed, left-handed twist; right-handed superhelix
  4. 443395Superfamily a.45.1: Glutathione S-transferase (GST), C-terminal domain [47616] (1 family) (S)
    this domains follows the thioredoxin-like N-terminal domain
  5. 443396Family a.45.1.1: Glutathione S-transferase (GST), C-terminal domain [47617] (16 proteins)

Proteins:

  1. 443397Chloride intracellular channel 1 (clic1) [69033] (1 species)
    similar to class theta enzymes; the N-domain undergoes a redox-controlled structural transition
  2. 443407Class alpha GST [81349] (8 species)
    1. 443408Species Blood fluke (Schistosoma haematobium) [TaxId:6185] [89060] (2 PDB entries)
    2. 443413Species Fasciola hepatica [TaxId:6192] [47634] (2 PDB entries)
    3. 443417Species Human (Homo sapiens), (a1-1) [TaxId:9606] [47625] (15 PDB entries)
    4. 443460Species Mouse (Mus musculus), (a1-1) [TaxId:10090] [47627] (2 PDB entries)
    5. 443465Species Mouse (Mus musculus), (a1-4) [TaxId:10090] [47628] (2 PDB entries)
    6. 443470Species Mouse (Mus musculus), (a2-2) [TaxId:10090] [89059] (1 PDB entry)
    7. 443473Species Rat (Rattus norvegicus), (a1-1) [TaxId:10116] [47626] (2 PDB entries)
    8. 443480Species Schistosoma japonicum [TaxId:6182] [47633] (9 PDB entries)
  3. 443491Class beta GST [81357] (3 species)
    1. 443492Species Escherichia coli [TaxId:562] [47638] (3 PDB entries)
    2. 443498Species Proteus mirabilis [TaxId:584] [47639] (2 PDB entries)
    3. 443504Species Sphingomonas paucimobilis [TaxId:13689] [47640] (1 PDB entry)
  4. 443509Class delta GST [81355] (5 species)
    formerly a part of class theta enzymes
    1. 443510Species African malaria mosquito (Anopheles gambiae), isozyme 1-6 [TaxId:7165] [101209] (1 PDB entry)
    2. 443513Species Mosquito (Anopheles dirus b), isozyme 1-3 [TaxId:123217] [74724] (1 PDB entry)
    3. 443520Species Mosquito (Anopheles dirus b), isozyme 1-4 [TaxId:123217] [74725] (1 PDB entry)
    4. 443523Species Mosquito (Anopheles dirus b), isozyme 1-5 [TaxId:123217] [101207] (1 PDB entry)
    5. 443525Species Mosquito (Anopheles dirus b), isozyme 1-6 [TaxId:123217] [101208] (1 PDB entry)
  5. 443530Class mu GST [81348] (3 species)
    1. 443531Species Chicken (Gallus gallus) [TaxId:9031] [47624] (2 PDB entries)
    2. 443538Species Human (Homo sapiens) [TaxId:9606] [47622] (7 PDB entries)
    3. 443564Species Rat (Rattus norvegicus) [TaxId:10116] [47623] (16 PDB entries)
  6. 443600Class omega GST [81352] (1 species)
  7. 443603Class phi GST [81356] (3 species)
    1. 443604Species Maize (Zea mays), type I [TaxId:4577] [47636] (2 PDB entries)
    2. 443611Species Maize (Zea mays), type III [TaxId:4577] [47637] (1 PDB entry)
    3. 443613Species Mouse-ear cress (Arabidopsis thaliana) [TaxId:3702] [47635] (2 PDB entries)
  8. 443617Class pi GST [81347] (3 species)
    1. 443618Species Human (Homo sapiens) [TaxId:9606] [47619] (36 PDB entries)
    2. 443702Species Mouse (Mus musculus) [TaxId:10090] [47621] (6 PDB entries)
    3. 443719Species Pig (Sus scrofa) [TaxId:9823] [47620] (1 PDB entry)
  9. 443722Class sigma GST [81351] (5 species)
    1. 443723Species Fruit fly (Drosophila melanogaster) [TaxId:7227] [81771] (1 PDB entry)
    2. 443726Species Heligmosomoides polygyrus [TaxId:6339] [109834] (1 PDB entry)
    3. 443735Species Human (Homo sapiens) [TaxId:9606] [89061] (2 PDB entries)
      synonym: hematopoietic prostaglandin D synthase
    4. 443744Species Rat (Rattus norvegicus) [TaxId:10116] [47630] (1 PDB entry)
      synonym: hematopoietic prostaglandin D synthase
    5. 443747Species Squid (Ommastrephes sloani pacificus) [TaxId:6634] [47631] (2 PDB entries)
  10. 443750Class tau GST [81354] (2 species)
    1. 443751Species Rice (Oryza sativa) [TaxId:4530] [89062] (1 PDB entry)
    2. 443756Species Wheat (Triticum tauschii l.) [74726] (1 PDB entry)
  11. 443760Class theta GST [81350] (1 species)
  12. 443768Class zeta GST [81353] (2 species)
    1. 443769Species Human (Homo sapiens) [TaxId:9606] [63555] (1 PDB entry)
      maleylacetoacetate isomerase
    2. 443771Species Mouse-ear cress (Arabidopsis thaliana) [TaxId:3702] [63556] (1 PDB entry)
  13. 443773Glutaredoxin 2 [63557] (1 species)
    similar to class zeta enzymes
  14. 443776GST-like domain of elongation factor 1-gamma [81772] (1 species)
  15. 443779Pf GST [101210] (1 species)
    cannot be assigned to any of the known GST classes
  16. 443787Yeast prion protein ure2p, nitrogen regulation fragment [47641] (1 species)
    similar to class phi enzymes

More info for Family a.45.1.1: Glutathione S-transferase (GST), C-terminal domain

Timeline for Family a.45.1.1: Glutathione S-transferase (GST), C-terminal domain: