SCOPe 2.08: Superfamily a.43.1: Ribbon-helix-helix

Lineage for Superfamily a.43.1: Ribbon-helix-helix

1. Root: SCOPe 2.08

2. Class a: All alpha proteins [46456] (290 folds)

3. Fold a.43: Ribbon-helix-helix [47597] (1 superfamily)
   core: 4 helices; array of 2 hairpins, opened

4. Superfamily a.43.1: Ribbon-helix-helix [47598] (12 families)
   formerly Met repressor-like; dimeric proteins; the N-termini form a small beta-sheet ribbon

Families:

1. a.43.1.1: Arc/Mnt-like phage repressors [47599] (2 proteins)

2. a.43.1.3: CopG-like [100970] (4 proteins)
   similar to the phage repressor family

3. a.43.1.4: Omega transcriptional repressor [100971] (2 proteins)
   plasmid-encoded, similar to the phage repressor family
   automatically mapped to Pfam PF07764

4. a.43.1.5: Met repressor, MetJ (MetR) [100972] (1 protein)
   automatically mapped to Pfam PF01340

5. a.43.1.6: NE0241-like [140544] (1 protein)
   contains extra C-terminal long helix; currently consists of an orphan protein

6. a.43.1.7: SeqA N-terminal domain-like [140547] (1 protein)
   N-terminal part of Pfam PF03925

7. a.43.1.8: Trafficking protein A-like [140550] (1 protein)

8. a.43.1.9: VCA0319-like [140553] (1 protein)
   COG4453; extended and extra C-terminal helices; potential component of the bi-partite system also including an acetyltransferase
   automatically mapped to Pfam PF08681

9. a.43.1.10: VirC2-like [158482] (1 protein)
   Pfam PF07181; duplicated ribbon-helix-helix motif; fold forms a trefoil knot

10. a.43.1.11: PutA pre-N-terminal region-like [158485] (2 proteins)
    in PutA it forms a separate ribbon-helix-helix domain connected to the N-terminal enzymatic domain by a flexible linker

11. a.43.1.12: MJ0366-like [158488] (1 protein)
    PfamB PB022101; duplicated ribbon-helix-helix motif; forms trefoil knot; predicted DNA binding
    automatically mapped to Pfam PF10802

12. a.43.1.0: automated matches [230594] (1 protein)
    not a true family

More info for Superfamily a.43.1: Ribbon-helix-helix

Timeline for Superfamily a.43.1: Ribbon-helix-helix:

• Superfamily a.43.1: Ribbon-helix-helix first appeared (with stable ids) in SCOP 1.55, called Superfamily a.43.1: Met repressor-like
  
• Superfamily a.43.1: Ribbon-helix-helix appears in SCOPe 2.07