SCOP 1.65: Family a.39.1.7: EF-hand modules in multidomain proteins

Lineage for Family a.39.1.7: EF-hand modules in multidomain proteins

1. Root: SCOP 1.65

2. Class a: All alpha proteins [46456] (179 folds)

3. Fold a.39: EF Hand-like [47472] (4 superfamilies)
   core: 4 helices; array of 2 hairpins, opened

4. Superfamily a.39.1: EF-hand [47473] (10 families)
   Duplication: consists of two EF-hand units: each is made of two helices connected with calcium-binding loop

5. Family a.39.1.7: EF-hand modules in multidomain proteins [47547] (4 proteins)

Proteins:

1. alpha-Actinin [63553] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [63554] (1 PDB entry)

2. Cbl [47561] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [47562] (3 PDB entries)

3. Dystrophin [47559] (1 species)
   probably lost calcium-binding function; contains extra helices in each domain

   • Species Human (Homo sapiens) [TaxId:9606] [47560] (2 PDB entries)

4. Phosphoinositide-specific phospholipase C, isozyme D1 (PLC-D!) [47548] (1 species)

   • Species Rat (Rattus norvegicus) [TaxId:10116] [47549] (10 PDB entries)

More info for Family a.39.1.7: EF-hand modules in multidomain proteins

Timeline for Family a.39.1.7: EF-hand modules in multidomain proteins:

• Family a.39.1.7: EF-hand modules in multidomain proteins first appeared (with stable ids) in SCOP 1.55
  
• Family a.39.1.7: EF-hand modules in multidomain proteins appears in SCOP 1.63
  
• Family a.39.1.7: EF-hand modules in multidomain proteins appears in SCOP 1.67
  
• Family a.39.1.7: EF-hand modules in multidomain proteins appears in the current release, SCOPe 2.08