Lineage for Family a.39.1.5: Calmodulin-like

  1. Root: SCOPe 2.01
  2. 901761Class a: All alpha proteins [46456] (284 folds)
  3. 914068Fold a.39: EF Hand-like [47472] (4 superfamilies)
    core: 4 helices; array of 2 hairpins, opened
  4. 914069Superfamily a.39.1: EF-hand [47473] (12 families) (S)
    Duplication: consists of two EF-hand units: each is made of two helices connected with calcium-binding loop
  5. 914403Family a.39.1.5: Calmodulin-like [47502] (24 proteins)
    Duplication: made with two pairs of EF-hands

Proteins:

  1. 914404Calcineurin B-like protein 2 [101182] (1 species)
  2. 914408Calcineurin regulatory subunit (B-chain) [47530] (2 species)
    1. 914409Species Cow (Bos taurus) [TaxId:9913] [47531] (2 PDB entries)
    2. 914413Species Human (Homo sapiens) [TaxId:9606] [47532] (3 PDB entries)
  3. 914418Calcium vector protein [47514] (1 species)
  4. 914424Calcium- and integrin-binding protein, CIB [47541] (1 species)
  5. 914430Calcium-dependent protein kinase sk5 CLD [109821] (1 species)
  6. 914434Calcium-regulated photoprotein [47512] (4 species)
    structurally most similar to sarcoplasmic calcium-binding protein
    1. 914435Species Hydrozoa (Obelia geniculata), obelin [TaxId:185004] [63542] (1 PDB entry)
    2. 914437Species Hydrozoa (Obelia longissima), obelin [TaxId:32570] [63541] (8 PDB entries)
      Uniprot Q27709
    3. 914446Species Jellyfish (Aequorea aequorea), aequorin [TaxId:168712] [47513] (1 PDB entry)
    4. 914449Species Jellyfish (Aequorea victoria), aequorin 1 [TaxId:6100] [116901] (1 PDB entry)
      Uniprot P07164 16-196
  7. 914451Calerythrin [101179] (1 species)
    structurally most similar to sarcoplasmic calcium-binding protein
  8. 914454Calmodulin [47516] (11 species)
    1. 914455Species African frog (Xenopus laevis) [TaxId:8355] [47521] (39 PDB entries)
    2. 914513Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [89052] (3 PDB entries)
    3. 914517Species Chicken (Gallus gallus) [TaxId:9031] [47520] (7 PDB entries)
      mutant with a two residue deletion in the central helix
    4. 914527Species Ciliate (Paramecium tetraurelia) [TaxId:5888] [47523] (4 PDB entries)
      Uniprot Q42478
    5. 914533Species Cow (Bos taurus) [TaxId:9913] [47518] (26 PDB entries)
      Uniprot P62157
    6. 914594Species Fruit fly (Drosophila melanogaster) [TaxId:7227] [47522] (9 PDB entries)
    7. 914608Species Human (Homo sapiens) [TaxId:9606] [47517] (17 PDB entries)
      Uniprot P02593
    8. 914654Species Nematode (Caenorhabditis elegans) [TaxId:6239] [89051] (1 PDB entry)
    9. 914656Species Norway rat (Rattus norvegicus) [TaxId:10116] [158477] (2 PDB entries)
    10. 914659Species Potato (Solanum tuberosum) [TaxId:4113] [109820] (1 PDB entry)
    11. 914661Species Rat (Rattus rattus) [TaxId:10117] [47519] (5 PDB entries)
      Uniprot P62161
  9. 914681Calmodulin-related protein NB-1 (CLP) [74721] (1 species)
  10. 914684Calmodulin-related protein T21P5.17 [109823] (1 species)
  11. 914687Caltractin (centrin 2) [89053] (2 species)
    1. 914688Species Green alga (Chlamydomonas reinhardtii) [TaxId:3055] [89055] (1 PDB entry)
    2. 914690Species Human (Homo sapiens) [TaxId:9606] [89054] (5 PDB entries)
  12. 914696Cdc4p [63543] (1 species)
  13. 914699EHCABP [69021] (1 species)
  14. 914705Frequenin (neuronal calcium sensor 1) [47535] (2 species)
    1. 914706Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [47536] (2 PDB entries)
    2. 914709Species Human (Homo sapiens) [TaxId:9606] [63545] (1 PDB entry)
  15. 914712Guanylate cyclase activating protein 2, GCAP-2 [47537] (1 species)
  16. 914715Kchip1, Kv4 potassium channel-interacting protein [101184] (2 species)
    1. 914716Species Human (Homo sapiens) [TaxId:9606] [116902] (1 PDB entry)
      Uniprot Q9NZI2
    2. 914718Species Norway rat (Rattus norvegicus) [TaxId:10116] [101185] (1 PDB entry)
  17. 914720Myosin Essential Chain [47524] (3 species)
    1. 914721Species Bay scallop (Aequipecten irradians) [TaxId:31199] [47525] (13 PDB entries)
      Uniprot P13543
    2. 914736Species Chicken (Gallus gallus) [TaxId:9031] [47526] (4 PDB entries)
    3. 914748Species Human (Homo sapiens) [TaxId:9606] [101181] (2 PDB entries)
  18. 914751Myosin Light Chain Mlc1p [81756] (1 species)
    light chain of class V myosin
  19. 914757Myosin Regulatory Chain [47527] (2 species)
    1. 914758Species Bay scallop (Aequipecten irradians) [TaxId:31199] [47528] (15 PDB entries)
      Uniprot P07291
    2. 914775Species Chicken (Gallus gallus) [TaxId:9031] [47529] (1 PDB entry)
  20. 914777Neurocalcin [47539] (1 species)
  21. 914781Recoverin [47533] (1 species)
    Calcium-myristoyl switch; only one EF-hand is functional
  22. 914794Sarcoplasmic calcium-binding protein [47509] (2 species)
    1. 914795Species Amphioxus (Branchiostoma lanceolatum) [TaxId:7740] [47511] (1 PDB entry)
    2. 914797Species Sandworm (Nereis diversicolor) [TaxId:126592] [47510] (2 PDB entries)
      Uniprot P04571
  23. 914801Troponin C [47503] (6 species)
    1. 914802Species Chicken (Gallus gallus) [TaxId:9031] [47504] (28 PDB entries)
      Uniprot P09860
    2. 914834Species Chicken (Gallus gallus), cardiac isoform [TaxId:9031] [47507] (1 PDB entry)
    3. 914836Species Human (Homo sapiens), cardiac isoform [TaxId:9606] [47508] (15 PDB entries)
    4. 914860Species Rabbit (Oryctolagus cuniculus) [TaxId:9986] [47506] (4 PDB entries)
    5. 914865Species Rainbow trout (Oncorhynchus mykiss) [TaxId:8022] [109819] (2 PDB entries)
      Uniprot Q7ZZB9 1-89
    6. 914868Species Turkey (Meleagris gallopavo) [TaxId:9103] [47505] (2 PDB entries)
  24. 914871automated matches [190064] (9 species)
    not a true protein
    1. 914872Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [188855] (2 PDB entries)
    2. 914878Species Bay scallop (Argopecten irradians) [TaxId:31199] [189156] (2 PDB entries)
    3. 914881Species Chicken (Gallus gallus) [TaxId:9031] [187205] (1 PDB entry)
    4. 914883Species Human (Homo sapiens) [TaxId:9606] [186813] (6 PDB entries)
    5. 914891Species Jellyfish (Aequorea victoria) [TaxId:6100] [186782] (4 PDB entries)
    6. 914900Species Mouse (Mus musculus) [TaxId:10090] [187204] (1 PDB entry)
    7. 914903Species Placopecten magellanicus [TaxId:6577] [189594] (3 PDB entries)
    8. 914916Species Scherffelia dubia [TaxId:3190] [189616] (1 PDB entry)
    9. 914918Species Todarodes pacificus [TaxId:6637] [189006] (1 PDB entry)

More info for Family a.39.1.5: Calmodulin-like

Timeline for Family a.39.1.5: Calmodulin-like: