Lineage for Family a.39.1.5: Calmodulin-like

  1. Root: SCOP 1.67
  2. 349259Class a: All alpha proteins [46456] (202 folds)
  3. 355182Fold a.39: EF Hand-like [47472] (4 superfamilies)
    core: 4 helices; array of 2 hairpins, opened
  4. 355183Superfamily a.39.1: EF-hand [47473] (10 families) (S)
    Duplication: consists of two EF-hand units: each is made of two helices connected with calcium-binding loop
  5. 355357Family a.39.1.5: Calmodulin-like [47502] (21 proteins)
    Duplication: made with two pairs of EF-hands

Proteins:

  1. 355358Calcineurin B-like protein 2 [101182] (1 species)
  2. 355361Calcineurin regulatory subunit (B-chain) [47530] (2 species)
    1. 355362Species Cow (Bos taurus) [TaxId:9913] [47531] (1 PDB entry)
    2. 355364Species Human (Homo sapiens) [TaxId:9606] [47532] (3 PDB entries)
  3. 355369Calcium vector protein [47514] (1 species)
  4. 355375Calcium- and integrin-binding protein, CIB [47541] (1 species)
  5. 355379Calcium-regulated photoprotein [47512] (3 species)
    structurally most similar to sarcoplasmic calcium-binding protein
    1. 355380Species Hydrozoa (Obelia geniculata), obelin [TaxId:185004] [63542] (1 PDB entry)
    2. 355382Species Hydrozoa (Obelia longissima), obelin [TaxId:32570] [63541] (4 PDB entries)
    3. 355387Species Jellyfish (Aequorea aequorea), aequorin [TaxId:168712] [47513] (1 PDB entry)
  6. 355390Calerythrin [101179] (1 species)
    structurally most similar to sarcoplasmic calcium-binding protein
  7. 355393Calmodulin [47516] (9 species)
    1. 355394Species African frog (Xenopus laevis) [TaxId:8355] [47521] (10 PDB entries)
    2. 355405Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [89052] (3 PDB entries)
    3. 355409Species Chicken (Gallus gallus) [TaxId:9031] [47520] (1 PDB entry)
      mutant with a two residue deletion in the central helix
    4. 355411Species Ciliate (Paramecium tetraurelia) [TaxId:5888] [47523] (4 PDB entries)
    5. 355417Species Cow (Bos taurus) [TaxId:9913] [47518] (16 PDB entries)
    6. 355441Species Drosophila melanogaster [TaxId:7227] [47522] (4 PDB entries)
    7. 355447Species Human (Homo sapiens) [TaxId:9606] [47517] (10 PDB entries)
    8. 355468Species Nematode (Caenorhabditis elegans) [TaxId:6239] [89051] (1 PDB entry)
    9. 355470Species Rat (Rattus rattus) [TaxId:10117] [47519] (3 PDB entries)
  8. 355477Calmodulin-related protein NB-1 (CLP) [74721] (1 species)
  9. 355480Caltractin (centrin 2) [89053] (2 species)
    1. 355481Species Green algae (Chlamydomonas reinhardtii) [TaxId:3055] [89055] (1 PDB entry)
    2. 355483Species Human (Homo sapiens) [TaxId:9606] [89054] (1 PDB entry)
  10. 355485Cdc4p [63543] (1 species)
  11. 355488EHCABP [69021] (1 species)
  12. 355492Frequenin (neuronal calcium sensor 1) [47535] (2 species)
    1. 355493Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [47536] (1 PDB entry)
    2. 355495Species Human (Homo sapiens) [TaxId:9606] [63545] (1 PDB entry)
  13. 355498Guanylate cyclase activating protein 2, GCAP-2 [47537] (1 species)
  14. 355501Kchip1, Kv4 potassium channel-interacting protein [101184] (1 species)
  15. 355504Myosin Essential Chain [47524] (3 species)
    1. 355505Species Bay scallop (Aequipecten irradians) [TaxId:31199] [47525] (11 PDB entries)
    2. 355518Species Chicken (Gallus gallus) [TaxId:9031] [47526] (3 PDB entries)
    3. 355528Species Human (Homo sapiens) [TaxId:9606] [101181] (1 PDB entry)
  16. 355530Myosin Light Chain Mlc1p [81756] (1 species)
    light chain of class V myosin
  17. 355536Myosin Regulatory Chain [47527] (2 species)
    1. 355537Species Bay scallop (Aequipecten irradians) [TaxId:31199] [47528] (11 PDB entries)
    2. 355550Species Chicken (Gallus gallus) [TaxId:9031] [47529] (1 PDB entry)
  18. 355552Neurocalcin [47539] (1 species)
  19. 355556Recoverin [47533] (1 species)
    Calcium-myristoyl switch; only one EF-hand is functional
  20. 355564Sarcoplasmic calcium-binding protein [47509] (2 species)
    1. 355565Species Amphioxus (Branchiostoma lanceolatum) [TaxId:7740] [47511] (1 PDB entry)
    2. 355567Species Sandworm (Nereis diversicolor) [TaxId:126592] [47510] (1 PDB entry)
  21. 355570Troponin C [47503] (5 species)
    1. 355571Species Chicken (Gallus gallus) [TaxId:9031] [47504] (24 PDB entries)
    2. 355599Species Chicken (Gallus gallus), cardiac isoform [TaxId:9031] [47507] (1 PDB entry)
    3. 355601Species Human (Homo sapiens), cardiac isoform [TaxId:9606] [47508] (8 PDB entries)
    4. 355612Species Rabbit (Oryctolagus cuniculus) [TaxId:9986] [47506] (4 PDB entries)
    5. 355617Species Turkey (Meleagris gallopavo) [TaxId:9103] [47505] (2 PDB entries)

More info for Family a.39.1.5: Calmodulin-like

Timeline for Family a.39.1.5: Calmodulin-like: