Class a: All alpha proteins [46456] (284 folds) |
Fold a.39: EF Hand-like [47472] (4 superfamilies) core: 4 helices; array of 2 hairpins, opened |
Superfamily a.39.1: EF-hand [47473] (12 families) Duplication: consists of two EF-hand units: each is made of two helices connected with calcium-binding loop |
a.39.1.1: Calbindin D9K [47474] (1 protein) made of two EF-hands only |
a.39.1.2: S100 proteins [47478] (2 proteins) dimer: subunits are made of two EF-hands |
a.39.1.3: Osteonectin [47489] (1 protein) 5 helices; two EF-hands plus one of additional helices in the N-terminal part |
a.39.1.4: Parvalbumin [47492] (3 proteins) 6-helices; array of 3 hairpins, closed made with two-helical hairpin and two EF-hands |
a.39.1.5: Calmodulin-like [47502] (24 proteins) Duplication: made with two pairs of EF-hands |
a.39.1.6: Eps15 homology domain (EH domain) [47543] (3 proteins) |
a.39.1.7: EF-hand modules in multidomain proteins [47547] (9 proteins) |
a.39.1.8: Penta-EF-hand proteins [63550] (6 proteins) |
a.39.1.9: Cbp40 (plasmodial specific CaII-binding protein LAV1-2) [81758] (1 protein) 4 EF-hands assembled in a compact structure like the Penta-EF-hand proteins; contains additional N-terminal all-alpha subdomain |
a.39.1.10: Polcalcin [89048] (3 proteins) calcium-binding pollen allergen; two EF-hands per subunit |
a.39.1.11: p25-alpha [140538] (2 proteins) Pfam PF05517; comprises two degenerate EF-hands and extra C-terminal helix, packed agains the bundle end |
a.39.1.0: automated matches [191396] (1 protein) not a true family |
Timeline for Superfamily a.39.1: EF-hand: