SCOPe 2.07: Fold a.39: EF Hand-like

Lineage for Fold a.39: EF Hand-like

1. Root: SCOPe 2.07

2. Class a: All alpha proteins [46456] (289 folds)

3. Fold a.39: EF Hand-like [47472] (4 superfamilies)
   core: 4 helices; array of 2 hairpins, opened

Superfamilies:

1. a.39.1: EF-hand [47473] (12 families)
   Duplication: consists of two EF-hand units: each is made of two helices connected with calcium-binding loop

2. a.39.2: Insect pheromone/odorant-binding proteins [47565] (2 families)
   the N-terminal extension, containing a few short helices, forms a flexible lid for the binding cavity

3. a.39.3: Cloroperoxidase [47571] (1 family)
   duplication: consists of 2 similar domains composed of 2 EF hand-like motifs each

4. a.39.4: Hypothetical protein MTH865 [69025] (1 family)
   automatically mapped to Pfam PF07747

More info for Fold a.39: EF Hand-like

Timeline for Fold a.39: EF Hand-like:

• Fold a.39: EF Hand-like first appeared (with stable ids) in SCOP 1.55
  
• Fold a.39: EF Hand-like appears in SCOPe 2.06
  
• Fold a.39: EF Hand-like appears in the current release, SCOPe 2.08