Lineage for Superfamily a.35.1: lambda repressor-like DNA-binding domains

  1. Root: SCOPe 2.02
  2. 1074916Class a: All alpha proteins [46456] (284 folds)
  3. 1087132Fold a.35: lambda repressor-like DNA-binding domains [47412] (1 superfamily)
    core: 4 helices; folded leaf, closed
  4. 1087133Superfamily a.35.1: lambda repressor-like DNA-binding domains [47413] (14 families) (S)

Families:

  1. 1087134a.35.1.1: POU-specific domain [47414] (3 proteins)
  2. 1087154a.35.1.2: Phage repressors [47419] (7 proteins)
    consists of different sequence families of HTH repressors of phage origins
  3. 1087227a.35.1.3: SinR domain-like [47432] (9 proteins)
  4. 1087289a.35.1.4: Cyanase N-terminal domain [47435] (1 protein)
    probably does not bind to DNA
  5. 1087332a.35.1.5: GalR/LacI-like bacterial regulator [47438] (4 proteins)
    lacks the first helix of canonical fold
    3 helices; bundle, partly opened, right-handed twist
  6. 1087398a.35.1.6: YdiL-like [109813] (2 proteins)
    contains extra C-terminal all-alpha dimerization subdomain; the dimer may bind DNA
  7. 1087409a.35.1.7: CUT domain [116891] (5 proteins)
    Pfam PF02376
  8. 1087429a.35.1.8: Probable transcriptional regulator VC1968, N-terminal domain [116898] (1 protein)
  9. 1087433a.35.1.9: Bacteriophage CII protein [140520] (1 protein)
    Pfam PF05269; a compact helix-swapped dimer of the canonical fold; includes the extra C-terminal teramerisation region (alpha-helix); in the tetramer-DNA complex only two of the four HTH motifs interact with DNA
  10. 1087448a.35.1.10: NE0471 C-terminal domain-like [140523] (1 protein)
  11. 1087453a.35.1.11: PrgX N-terminal domain-like [140526] (1 protein)
    Part of Pfam PF01381
  12. 1087496a.35.1.12: EDF1-like [140529] (1 protein)
    part of Pfam PF01381
  13. 1087500a.35.1.13: NE1354 [140532] (2 proteins)
    contains extra C-terminal dimerisation arm (beta-strand)
  14. 1087509a.35.1.0: automated matches [191534] (1 protein)
    not a true family

More info for Superfamily a.35.1: lambda repressor-like DNA-binding domains

Timeline for Superfamily a.35.1: lambda repressor-like DNA-binding domains: