Class a: All alpha proteins [46456] (289 folds) |
Fold a.26: 4-helical cytokines [47265] (1 superfamily) core: 4 helices; bundle, closed; left-handed twist; 2 crossover connections |
Superfamily a.26.1: 4-helical cytokines [47266] (4 families) there are two different topoisomers of this fold with different entanglements of the two crossover connections |
Family a.26.1.2: Short-chain cytokines [47286] (14 proteins) |
Protein Interleukin-2 (IL-2) [47301] (1 species) |
Species Human (Homo sapiens) [TaxId:9606] [47302] (16 PDB entries) |
Domain d1irla_: 1irl A: [16883] mutant |
Domain d1m47a_: 1m47 A: [74442] complexed with so4 |
Domain d1m48a_: 1m48 A: [74443] complexed with frg |
Domain d1m48b_: 1m48 B: [74444] complexed with frg |
Domain d1m49a_: 1m49 A: [74445] complexed with cmm |
Domain d1m49b_: 1m49 B: [74446] complexed with cmm |
Domain d1m4aa_: 1m4a A: [74447] complexed with gol, mpe |
Domain d1m4ba_: 1m4b A: [74448] complexed with nmp |
Domain d1m4ca_: 1m4c A: [74449] |
Domain d1m4cb_: 1m4c B: [74450] |
Domain d1nbpa_: 1nbp A: [80392] complexed with mhc, so4 |
Domain d1pw6a_: 1pw6 A: [95200] complexed with a small molecule inhibitor complexed with frb, so4 |
Domain d1pw6b_: 1pw6 B: [95201] complexed with a small molecule inhibitor complexed with frb, so4 |
Domain d1py2a_: 1py2 A: [95319] complexed with a small molecule inhibitor complexed with frh, zn |
Domain d1py2b_: 1py2 B: [95320] complexed with a small molecule inhibitor complexed with frh, zn |
Domain d1py2c_: 1py2 C: [95321] complexed with a small molecule inhibitor complexed with frh, zn |
Domain d1py2d_: 1py2 D: [95322] complexed with a small molecule inhibitor complexed with frh, zn |
Domain d1qvna_: 1qvn A: [161678] automated match to d1irla_ complexed with fri, zn |
Domain d1qvnb_: 1qvn B: [161679] automated match to d1irla_ complexed with fri, zn |
Domain d1qvnc_: 1qvn C: [161680] automated match to d1irla_ complexed with fri, zn |
Domain d1qvnd_: 1qvn D: [161681] automated match to d1irla_ complexed with fri, zn |
Domain d1z92a_: 1z92 A: [124737] Other proteins in same PDB: d1z92b1, d1z92b2, d1z92b3 automated match to d1irl__ |
Domain d2erjd_: 2erj D: [132294] Other proteins in same PDB: d2erja1, d2erja2, d2erjb1, d2erjb2, d2erjb3, d2erjc1, d2erjc2, d2erje1, d2erje2, d2erjf1, d2erjf2, d2erjf3, d2erjg1, d2erjg2 automated match to d1irla_ complexed with nag |
Domain d2erjh_: 2erj H: [132301] Other proteins in same PDB: d2erja1, d2erja2, d2erjb1, d2erjb2, d2erjb3, d2erjc1, d2erjc2, d2erje1, d2erje2, d2erjf1, d2erjf2, d2erjf3, d2erjg1, d2erjg2 automated match to d1irla_ complexed with nag |
Domain d3inkc_: 3ink C: [16881] |
Domain d3inkd_: 3ink D: [16882] |
Domain d3qb1a_: 3qb1 A: [248836] automated match to d1irla_ mutant |
Domain d3qb1b_: 3qb1 B: [248837] automated match to d1irla_ mutant |
Domain d3qb1c_: 3qb1 C: [248838] automated match to d1irla_ mutant |
Domain d3qb1d_: 3qb1 D: [248839] automated match to d1irla_ mutant |
Domain d3qb1e_: 3qb1 E: [248840] automated match to d1irla_ mutant |
Domain d3qb1f_: 3qb1 F: [248841] automated match to d1irla_ mutant |
Domain d3qb1g_: 3qb1 G: [248842] automated match to d1irla_ mutant |
Domain d3qb1h_: 3qb1 H: [248843] automated match to d1irla_ mutant |
Timeline for Species Human (Homo sapiens) [TaxId:9606] from a.26.1.2 Interleukin-2 (IL-2):