Lineage for Species: Human (Homo sapiens) [TaxId: 9606]

  1. Root: SCOPe 2.04
  2. 1473060Class a: All alpha proteins [46456] (285 folds)
  3. 1486907Fold a.26: 4-helical cytokines [47265] (1 superfamily)
    core: 4 helices; bundle, closed; left-handed twist; 2 crossover connections
  4. 1486908Superfamily a.26.1: 4-helical cytokines [47266] (4 families) (S)
    there are two different topoisomers of this fold with different entanglements of the two crossover connections
  5. 1486997Family a.26.1.2: Short-chain cytokines [47286] (14 proteins)
  6. Protein Macrophage colony-stimulating factor (M-CSF) [47295] (1 species)
    forms dimer similar to the Flt3 ligand and SCF dimers
  7. Species Human (Homo sapiens) [TaxId:9606] [47296] (1 PDB entry)

PDB entry in Species: Human (Homo sapiens) [TaxId: 9606]:

More info for Species Human (Homo sapiens) [TaxId:9606] from a.26.1.2 Macrophage colony-stimulating factor (M-CSF)

Timeline for Species Human (Homo sapiens) [TaxId:9606] from a.26.1.2 Macrophage colony-stimulating factor (M-CSF):