Lineage for Protein: Ciliary neurotrophic factor (CNTF)

  1. Root: SCOPe 2.08
  2. 2685877Class a: All alpha proteins [46456] (290 folds)
  3. 2705447Fold a.26: 4-helical cytokines [47265] (1 superfamily)
    core: 4 helices; bundle, closed; left-handed twist; 2 crossover connections
  4. 2705448Superfamily a.26.1: 4-helical cytokines [47266] (4 families) (S)
    there are two different topoisomers of this fold with different entanglements of the two crossover connections
  5. 2705449Family a.26.1.1: Long-chain cytokines [47267] (10 proteins)
  6. 2705450Protein Ciliary neurotrophic factor (CNTF) [47280] (1 species)

Species:

  • 2705451Human (Homo sapiens) [TaxId:9606] [47281] (1 PDB entry)
    • Domains for 1cnt:
      1. 2705452Domain d1cnt1_: 1cnt 1: [16840]
        complexed with so4, yb
        missing some secondary structures that made up less than one-third of the common domain
      2. 2705453Domain d1cnt2_: 1cnt 2: [16841]
        complexed with so4, yb
        missing some secondary structures that made up less than one-third of the common domain
      3. 2705454Domain d1cnt3_: 1cnt 3: [16842]
        complexed with so4, yb
        missing some secondary structures that made up less than one-third of the common domain
      4. 2705455Domain d1cnt4_: 1cnt 4: [16843]
        complexed with so4, yb
        missing some secondary structures that made up less than one-third of the common domain

More info for Protein Ciliary neurotrophic factor (CNTF) from a.26.1.1: Long-chain cytokines

Timeline for Protein Ciliary neurotrophic factor (CNTF) from a.26.1.1: Long-chain cytokines: