SCOPe 2.07: Species: Human (Homo sapiens) [TaxId: 9606]

Root: SCOPe 2.07
Class a: All alpha proteins [46456] (289 folds)
Fold a.26: 4-helical cytokines [47265] (1 superfamily)
core: 4 helices; bundle, closed; left-handed twist; 2 crossover connections
Superfamily a.26.1: 4-helical cytokines [47266] (4 families)
there are two different topoisomers of this fold with different entanglements of the two crossover connections
Family a.26.1.1: Long-chain cytokines [47267] (10 proteins)
Protein Interleukin-6 [47272] (2 species)
Species Human (Homo sapiens) [TaxId:9606] [47273] (9 PDB entries)

Domain(s) for 1alu:
- Domain d1alua_: 1alu A: [16826]
  complexed with so4, tla
Domain(s) for 1il6:
- Domain d1il6a_: 1il6 A: [16827]
Domain(s) for 1p9m:
- Domain d1p9mb_: 1p9m B: [87994]
  Other proteins in same PDB: d1p9ma1, d1p9ma2, d1p9ma3, d1p9mc1, d1p9mc2
Domain(s) for 2il6:
- Domain d2il6a_: 2il6 A: [16828]
Domain(s) for 4cni:
1. Domain d4cnic_: 4cni C: [256633]
  Other proteins in same PDB: d4cnib1, d4cnib2, d4cnil1, d4cnil2
  automated match to d4ni9a_
  complexed with so4, tam
2. Domain d4cnid_: 4cni D: [256634]
  Other proteins in same PDB: d4cnib1, d4cnib2, d4cnil1, d4cnil2
  automated match to d4ni9a_
  complexed with so4, tam
Domain(s) for 4ni7:
- Domain d4ni7a_: 4ni7 A: [236231]
  automated match to d1alua_
  protein/DNA complex; complexed with na
Domain(s) for 4ni9:
1. Domain d4ni9a_: 4ni9 A: [236232]
  automated match to d1alua_
  protein/DNA complex; complexed with na
2. Domain d4ni9c_: 4ni9 C: [236233]
  automated match to d1alua_
  protein/DNA complex; complexed with na
Domain(s) for 4o9h:
- Domain d4o9ha_: 4o9h A: [271394]
  Other proteins in same PDB: d4o9hl1, d4o9hl2
  automated match to d1alua_
Domain(s) for 4zs7:
- Domain d4zs7a_: 4zs7 A: [317121]
  Other proteins in same PDB: d4zs7l1, d4zs7l2
  automated match to d4cnic_

Timeline for Species Human (Homo sapiens) [TaxId:9606] from a.26.1.1 Interleukin-6:

Species Human (Homo sapiens) [TaxId:9606] from a.26.1.1 Interleukin-6 first appeared (with stable ids) in SCOP 1.55
Species Human (Homo sapiens) [TaxId:9606] from a.26.1.1 Interleukin-6 appears in SCOPe 2.06
Species Human (Homo sapiens) [TaxId:9606] from a.26.1.1 Interleukin-6 appears in the current release, SCOPe 2.08