SCOPe 2.08: Protein: Ribonucleotide reductase R2

Lineage for Protein: Ribonucleotide reductase R2

Root: SCOPe 2.08
Class a: All alpha proteins [46456] (290 folds)
Fold a.25: Ferritin-like [47239] (6 superfamilies)
core: 4 helices; bundle, closed, left-handed twist; 1 crossover connection
Superfamily a.25.1: Ferritin-like [47240] (10 families)
contains bimetal-ion centre in the middle of the bundle
Family a.25.1.2: Ribonucleotide reductase-like [47253] (9 proteins)
Protein Ribonucleotide reductase R2 [47257] (10 species)

Species:

Baker's yeast (Saccharomyces cerevisiae), Y2 [TaxId:4932] [88795] (2 PDB entries)
Uniprot P09938
1. Domain for 1jk0:
  - Domain d1jk0a_: 1jk0 A: [63142]
    heterodimer with Y4 isoform
    complexed with zn
2. Domains for 1smq:
  1. Domain d1smqa_: 1smq A: [105766]
  2. Domain d1smqb_: 1smq B: [105767]
  3. Domain d1smqc_: 1smq C: [105768]
  4. Domain d1smqd_: 1smq D: [105769]
Baker's yeast (Saccharomyces cerevisiae), Y4 [TaxId:4932] [88796] (2 PDB entries)
Uniprot P49723
1. Domain for 1jk0:
  - Domain d1jk0b_: 1jk0 B: [63143]
    heterodimer with Y2 isoform
    complexed with zn
2. Domains for 1sms:
  1. Domain d1smsa_: 1sms A: [105770]
    complexed with hg
  2. Domain d1smsb_: 1sms B: [105771]
    complexed with hg
Chlamydia trachomatis [TaxId:813] [109786] (1 PDB entry)
Uniprot O84835
- Domain for 1syy:
  - Domain d1syya_: 1syy A: [106126]
    complexed with fe, pb
Corynebacterium ammoniagenes [TaxId:1697] [69006] (6 PDB entries)
1. Domains for 1kgn:
  1. Domain d1kgna_: 1kgn A: [68584]
    complexed with fe
  2. Domain d1kgnb_: 1kgn B: [68585]
    complexed with fe
  3. Domain d1kgnc_: 1kgn C: [68586]
    complexed with fe
  4. Domain d1kgnd_: 1kgn D: [68587]
    complexed with fe
2. Domains for 1kgo:
  1. Domain d1kgoa_: 1kgo A: [68588]
    complexed with fe2
  2. Domain d1kgob_: 1kgo B: [68589]
    complexed with fe2
  3. Domain d1kgoc_: 1kgo C: [68590]
    complexed with fe2
  4. Domain d1kgod_: 1kgo D: [68591]
    complexed with fe2
3. Domains for 1kgp:
  1. Domain d1kgpa_: 1kgp A: [68592]
    complexed with mn
  2. Domain d1kgpb_: 1kgp B: [68593]
    complexed with mn
  3. Domain d1kgpc_: 1kgp C: [68594]
    complexed with mn
  4. Domain d1kgpd_: 1kgp D: [68595]
    complexed with mn
4. Domains for 1oqu:
  1. Domain d1oqua_: 1oqu A: [93435]
    complexed with act, fe, oxy
  2. Domain d1oqub_: 1oqu B: [93436]
    complexed with act, fe, oxy
  3. Domain d1oquc_: 1oqu C: [93437]
    complexed with act, fe, oxy
  4. Domain d1oqud_: 1oqu D: [93438]
    complexed with act, fe, oxy
5. Domains for 3dhz:
  1. Domain d3dhza_: 3dhz A: [157741]
    automated match to d1oquc_
    complexed with fe2
  2. Domain d3dhzb_: 3dhz B: [157742]
    automated match to d1oquc_
    complexed with fe2
6. Domains for 3mjo:
  1. Domain d3mjoa_: 3mjo A: [181304]
    automated match to d1kgna_
    complexed with mn3
  2. Domain d3mjob_: 3mjo B: [181305]
    automated match to d1kgna_
    complexed with mn3
Escherichia coli [TaxId:562] [47258] (24 PDB entries)
1. Domains for 1av8:
  1. Domain d1av8a_: 1av8 A: [16796]
    complexed with feo
  2. Domain d1av8b_: 1av8 B: [16797]
    complexed with feo
2. Domains for 1biq:
  1. Domain d1biqa_: 1biq A: [16786]
    complexed with fe, fe2, hg, oh; mutant
  2. Domain d1biqb_: 1biq B: [16787]
    complexed with fe, fe2, hg, oh; mutant
3. Domains for 1jpr:
  1. Domain d1jpra_: 1jpr A: [63224]
    complexed with hg, mn
  2. Domain d1jprb_: 1jpr B: [63225]
    complexed with hg, mn
4. Domains for 1jqc:
  1. Domain d1jqca_: 1jqc A: [63229]
    complexed with hg, mn
  2. Domain d1jqcb_: 1jqc B: [63230]
    complexed with hg, mn
5. Domains for 1mrr:
  1. Domain d1mrra_: 1mrr A: [16794]
    complexed with hg, mn
  2. Domain d1mrrb_: 1mrr B: [16795]
    complexed with hg, mn
6. Domains for 1mxr:
  1. Domain d1mxra_: 1mxr A: [85197]
    complexed with fe, gol, hg
  2. Domain d1mxrb_: 1mxr B: [85198]
    complexed with fe, gol, hg
7. Domains for 1pfr:
  1. Domain d1pfra_: 1pfr A: [16790]
    complexed with fe, hg
  2. Domain d1pfrb_: 1pfr B: [16791]
    complexed with fe, hg
8. Domains for 1pim:
  1. Domain d1pima_: 1pim A: [88117]
    complexed with fe, hg; mutant
  2. Domain d1pimb_: 1pim B: [88118]
    complexed with fe, hg; mutant
9. Domains for 1piu:
  1. Domain d1piua_: 1piu A: [88119]
    complexed with fe, hg, o; mutant
  2. Domain d1piub_: 1piu B: [88120]
    complexed with fe, hg, o; mutant
10. Domains for 1piy:
  1. Domain d1piya_: 1piy A: [94710]
    complexed with fe, hg
  2. Domain d1piyb_: 1piy B: [94711]
    complexed with fe, hg
11. Domains for 1piz:
  1. Domain d1piza_: 1piz A: [94712]
    complexed with fe, hg; mutant
  2. Domain d1pizb_: 1piz B: [94713]
    complexed with fe, hg; mutant
12. Domains for 1pj0:
  1. Domain d1pj0a_: 1pj0 A: [94714]
    complexed with fe, hg; mutant
  2. Domain d1pj0b_: 1pj0 B: [94715]
    complexed with fe, hg; mutant
13. Domains for 1pj1:
  1. Domain d1pj1a_: 1pj1 A: [94716]
    complexed with fe, hg
  2. Domain d1pj1b_: 1pj1 B: [94717]
    complexed with fe, hg
14. Domains for 1pm2:
  1. Domain d1pm2a_: 1pm2 A: [94887]
    complexed with hg, mn; mutant
  2. Domain d1pm2b_: 1pm2 B: [94888]
    complexed with hg, mn; mutant
15. Domains for 1r65:
  1. Domain d1r65a_: 1r65 A: [97144]
    complexed with fe2, hg
  2. Domain d1r65b_: 1r65 B: [97145]
    complexed with fe2, hg
16. Domains for 1rib:
  1. Domain d1riba_: 1rib A: [16788]
    complexed with feo
  2. Domain d1ribb_: 1rib B: [16789]
    complexed with feo
17. Domains for 1rnr:
  1. Domain d1rnra_: 1rnr A: [16798]
    complexed with fe, hg
  2. Domain d1rnrb_: 1rnr B: [16799]
    complexed with fe, hg
18. Domains for 1rsr:
  1. Domain d1rsra_: 1rsr A: [97815]
    complexed with azi, fe2, hg; mutant
  2. Domain d1rsrb_: 1rsr B: [97816]
    complexed with azi, fe2, hg; mutant
19. Domains for 1rsv:
  1. Domain d1rsva_: 1rsv A: [97817]
    complexed with azi, fe, hg; mutant
  2. Domain d1rsvb_: 1rsv B: [97818]
    complexed with azi, fe, hg; mutant
20. Domains for 1xik:
  1. Domain d1xika_: 1xik A: [16784]
    complexed with fe2, hg
  2. Domain d1xikb_: 1xik B: [16785]
    complexed with fe2, hg
21. Domains for 1yfd:
  1. Domain d1yfda1: 1yfd A:1-340 [123059]
    complexed with feo, hg; mutant
  2. Domain d1yfdb_: 1yfd B: [123060]
    automated match to d1yfda1
    complexed with feo, hg; mutant
22. Domain for 2alx:
  - Domain d2alxa_: 2alx A: [126986]
    automated match to d1av8a_
    complexed with hg, mn
23. Domains for 2av8:
  1. Domain d2av8a_: 2av8 A: [16792]
    complexed with fe2, feo; mutant
  2. Domain d2av8b_: 2av8 B: [16793]
    complexed with fe2, feo; mutant
24. Domains for 2xof:
  1. Domain d2xofa_: 2xof A: [207288]
    automated match to d1jqcb_
    complexed with feo
  2. Domain d2xofb_: 2xof B: [207289]
    automated match to d1jqcb_
    complexed with feo
Escherichia coli [TaxId:745156] [318807] (3 PDB entries)
1. Domain for 5ci0:
  - Domain d5ci0a_: 5ci0 A: [318698]
    automated match to d1jqcb_
    complexed with feo, so4
2. Domain for 5ci1:
  - Domain d5ci1a_: 5ci1 A: [318728]
    automated match to d1jqcb_
    complexed with cl, feo, so4
3. Domain for 5ci4:
  - Domain d5ci4a_: 5ci4 A: [318808]
    automated match to d1jqcb_
    complexed with feo, so4
Human (Homo sapiens), RRM2 [TaxId:9606] [158401] (1 PDB entry)
Uniprot P31350 66-350
- Domain for 2uw2:
  - Domain d2uw2a1: 2uw2 A:66-350 [152205]
    complexed with fe
Mouse (Mus musculus) [TaxId:10090] [47260] (5 PDB entries)
Uniprot P11157
1. Domain for 1h0n:
  - Domain d1h0na_: 1h0n A: [70844]
    complexed with co
2. Domain for 1h0o:
  - Domain d1h0oa_: 1h0o A: [70845]
    complexed with co
3. Domain for 1w68:
  - Domain d1w68a_: 1w68 A: [109216]
    complexed with feo
4. Domain for 1w69:
  - Domain d1w69a_: 1w69 A: [109217]
    complexed with acy, fe2
5. Domain for 1xsm:
  - Domain d1xsma_: 1xsm A: [16804]
    complexed with fe
Mycobacterium tuberculosis [TaxId:1773] [109787] (1 PDB entry)
Uniprot Q50549 10-291
- Domains for 1uzr:
  1. Domain d1uzra_: 1uzr A: [108178]
    complexed with cit, fe, gol
  2. Domain d1uzrb_: 1uzr B: [108179]
    complexed with cit, fe, gol
  3. Domain d1uzrc_: 1uzr C: [108180]
    complexed with cit, fe, gol
Salmonella typhimurium [TaxId:90371] [47259] (3 PDB entries)
1. Domains for 1r2f:
  1. Domain d1r2fa_: 1r2f A: [16800]
    complexed with fe
  2. Domain d1r2fb_: 1r2f B: [16801]
    complexed with fe
2. Domains for 2bq1:
  1. Domain d2bq1i1: 2bq1 I:6-288 [128957]
    Other proteins in same PDB: d2bq1e1, d2bq1e2, d2bq1f1, d2bq1f2
    automatically matched to d2r2fa_
    protein/DNA complex; complexed with dgt, fe, mg
  2. Domain d2bq1j1: 2bq1 J:6-286 [128958]
    Other proteins in same PDB: d2bq1e1, d2bq1e2, d2bq1f1, d2bq1f2
    automatically matched to d2r2fa_
    protein/DNA complex; complexed with dgt, fe, mg
3. Domains for 2r2f:
  1. Domain d2r2fa_: 2r2f A: [16802]
    complexed with feo
  2. Domain d2r2fb_: 2r2f B: [16803]
    complexed with feo

More info for Protein Ribonucleotide reductase R2 from a.25.1.2: Ribonucleotide reductase-like

Timeline for Protein Ribonucleotide reductase R2 from a.25.1.2: Ribonucleotide reductase-like:

Protein Ribonucleotide reductase R2 from a.25.1.2: Ribonucleotide reductase-like first appeared (with stable ids) in SCOP 1.55
Protein Ribonucleotide reductase R2 from a.25.1.2: Ribonucleotide reductase-like appears in SCOPe 2.07