SCOP 1.67: Family a.22.1.1: Nucleosome core histones

Lineage for Family a.22.1.1: Nucleosome core histones

1. Root: SCOP 1.67

2. Class a: All alpha proteins [46456] (202 folds)

3. Fold a.22: Histone-fold [47112] (1 superfamily)
   core: 3 helices; long middle helix is flanked at each end with shorter ones

4. Superfamily a.22.1: Histone-fold [47113] (3 families)

5. Family a.22.1.1: Nucleosome core histones [47114] (4 proteins)
   form octamers composed of two copies of each of the four histones

Proteins:

1. Histone H2A [47115] (4 species)

   1. Species African clawed frog (Xenopus laevis) [TaxId:8355] [47117] (19 PDB entries)

   2. Species Baker's yeast (Saccharomyces cerevisiae), H2A.1 [TaxId:4932] [68984] (1 PDB entry)

   3. Species Chicken (Gallus gallus), erythrocytes [TaxId:9031] [47116] (4 PDB entries)

   4. Species Human (Homo sapiens), variant H2A.Z [TaxId:9606] [47118] (1 PDB entry)

2. Histone H2B [47119] (3 species)

   1. Species African clawed frog (Xenopus laevis) [TaxId:8355] [47121] (20 PDB entries)

   2. Species Baker's yeast (Saccharomyces cerevisiae), H2B.2 [TaxId:4932] [68985] (1 PDB entry)

   3. Species Chicken (Gallus gallus), erythrocytes [TaxId:9031] [47120] (4 PDB entries)

3. Histone H3 [47122] (3 species)

   1. Species African clawed frog (Xenopus laevis) [TaxId:8355] [47124] (20 PDB entries)

   2. Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [68986] (1 PDB entry)

   3. Species Chicken (Gallus gallus), erythrocytes [TaxId:9031] [47123] (4 PDB entries)

4. Histone H4 [47125] (4 species)

   1. Species African clawed frog (Xenopus laevis) [TaxId:8355] [47127] (19 PDB entries)

   2. Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [68987] (1 PDB entry)

   3. Species Chicken (Gallus gallus), erythrocytes [TaxId:9031] [47126] (4 PDB entries)

   4. Species Mouse (Mus musculus) [TaxId:10090] [47128] (1 PDB entry)

More info for Family a.22.1.1: Nucleosome core histones

Timeline for Family a.22.1.1: Nucleosome core histones:

• Family a.22.1.1: Nucleosome core histones first appeared (with stable ids) in SCOP 1.55
  
• Family a.22.1.1: Nucleosome core histones appears in SCOP 1.65
  
• Family a.22.1.1: Nucleosome core histones appears in SCOP 1.69
  
• Family a.22.1.1: Nucleosome core histones appears in the current release, SCOPe 2.08