Lineage for Superfamily a.22.1: Histone-fold

  1. Root: SCOPe 2.01
  2. 901761Class a: All alpha proteins [46456] (284 folds)
  3. 909266Fold a.22: Histone-fold [47112] (1 superfamily)
    core: 3 helices; long middle helix is flanked at each end with shorter ones
  4. 909267Superfamily a.22.1: Histone-fold [47113] (4 families) (S)


  1. 909268a.22.1.1: Nucleosome core histones [47114] (6 proteins)
    form octamers composed of two copies of each of the four histones
  2. 909650a.22.1.2: Archaeal histone [47129] (1 protein)
  3. 909666a.22.1.3: TBP-associated factors, TAFs [47134] (13 proteins)
  4. 909724a.22.1.4: Bacterial histone-fold protein [101318] (3 proteins)
    duplication: two repeats of histone fold are arranged as subunits in the archael histone dimer; new structure from Thermus thermophilus (1wws) comprised of dimers similar the to the H3-H4 tetramer

More info for Superfamily a.22.1: Histone-fold

Timeline for Superfamily a.22.1: Histone-fold: