Class a: All alpha proteins [46456] (226 folds) |
Fold a.22: Histone-fold [47112] (1 superfamily) core: 3 helices; long middle helix is flanked at each end with shorter ones |
Superfamily a.22.1: Histone-fold [47113] (4 families) |
a.22.1.1: Nucleosome core histones [47114] (4 proteins) form octamers composed of two copies of each of the four histones |
a.22.1.2: Archaeal histone [47129] (1 protein) |
a.22.1.3: TBP-associated factors, TAFs [47134] (11 proteins) |
a.22.1.4: Bacterial histone-fold protein [101318] (1 protein) duplication: two repeats of histone fold are arranged as subunits in the archael histone dimer; new structure from Thermus thermophilus (1wws) comprised of dimers similar the to the H3-H4 tetramer |
Timeline for Superfamily a.22.1: Histone-fold: