Lineage for Superfamily a.4.6: C-terminal effector domain of the bipartite response regulators

  1. Root: SCOP 1.67
  2. 349259Class a: All alpha proteins [46456] (202 folds)
  3. 351236Fold a.4: DNA/RNA-binding 3-helical bundle [46688] (12 superfamilies)
    core: 3-helices; bundle, closed or partly opened, right-handed twist; up-and down
  4. 352180Superfamily a.4.6: C-terminal effector domain of the bipartite response regulators [46894] (3 families) (S)
    binds to DNA and RNA polymerase; the N-terminal, receiver domain belongs to the CheY family

Families:

  1. 352181a.4.6.1: PhoB-like [46895] (3 proteins)
    contains 4-stranded meander beta-sheet in the N-terminal extension
  2. 352199a.4.6.2: GerE-like (LuxR/UhpA family of transcriptional regulators) [46900] (4 proteins)
    contains additional, fourth helix in the C-terminal extension
  3. 352230a.4.6.3: Spo0A [46903] (1 protein)
    elaborated with additional helices

More info for Superfamily a.4.6: C-terminal effector domain of the bipartite response regulators

Timeline for Superfamily a.4.6: C-terminal effector domain of the bipartite response regulators: