SCOPe 2.08: Family a.4.5.23: Interferon regulatory factor

Lineage for Family a.4.5.23: Interferon regulatory factor

1. Root: SCOPe 2.08

2. Class a: All alpha proteins [46456] (290 folds)

3. Fold a.4: DNA/RNA-binding 3-helical bundle [46688] (14 superfamilies)
   core: 3-helices; bundle, closed or partly opened, right-handed twist; up-and down

4. Superfamily a.4.5: 'Winged helix' DNA-binding domain [46785] (86 families)
   contains a small beta-sheet (wing)

5. Family a.4.5.23: Interferon regulatory factor [46877] (4 proteins)
   Pfam PF00605

Proteins:

1. Interferon regulatory factor 1 (IRF-1) [46878] (1 species)

   • Species Mouse (Mus musculus) [TaxId:10090] [46879] (1 PDB entry)

2. Interferon regulatory factor 3, IRF-3 [116791] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [116792] (3 PDB entries)
     Uniprot Q14653 3-112

3. Interferon regulatory factor-2, IRF-2 [46880] (1 species)

   • Species Mouse (Mus musculus) [TaxId:10090] [46881] (3 PDB entries)

4. automated matches [191301] (1 species)
   not a true protein

   • Species Human (Homo sapiens) [TaxId:9606] [189980] (1 PDB entry)

More info for Family a.4.5.23: Interferon regulatory factor

Timeline for Family a.4.5.23: Interferon regulatory factor:

• Family a.4.5.23: Interferon regulatory factor first appeared (with stable ids) in SCOP 1.55
  
• Family a.4.5.23: Interferon regulatory factor appears in SCOPe 2.07