SCOPe 2.06: Family a.4.5.14: Forkhead DNA-binding domain

Lineage for Family a.4.5.14: Forkhead DNA-binding domain

1. Root: SCOPe 2.06

2. Class a: All alpha proteins [46456] (289 folds)

3. Fold a.4: DNA/RNA-binding 3-helical bundle [46688] (14 superfamilies)
   core: 3-helices; bundle, closed or partly opened, right-handed twist; up-and down

4. Superfamily a.4.5: "Winged helix" DNA-binding domain [46785] (85 families)
   contains a small beta-sheet (wing)

5. Family a.4.5.14: Forkhead DNA-binding domain [46832] (7 proteins)

Proteins:

1. Adipocyte-transcription factor FREAC-11 (s12, fkh-14) [46835] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [46836] (1 PDB entry)

2. Afx (Foxo4) [46833] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [46834] (2 PDB entries)

3. Forkhead box protein P2, FOXP2 [140265] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [140266] (1 PDB entry)
     Uniprot O15409 503-584

4. Genesis [46837] (1 species)

   • Species Norway rat (Rattus norvegicus) [TaxId:10116] [46838] (2 PDB entries)

5. HFH-1 (HNF-3 forkhead homolog-1) [46839] (1 species)

   • Species Norway rat (Rattus norvegicus) [TaxId:10116] [46840] (1 PDB entry)

6. Interleukin enhancer binding factor [88984] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [88985] (1 PDB entry)

7. automated matches [190243] (2 species)
   not a true protein

   1. Species Human (Homo sapiens) [TaxId:9606] [187016] (8 PDB entries)

   2. Species Mouse (Mus musculus) [TaxId:10090] [255024] (2 PDB entries)

More info for Family a.4.5.14: Forkhead DNA-binding domain

Timeline for Family a.4.5.14: Forkhead DNA-binding domain:

• Family a.4.5.14: Forkhead DNA-binding domain first appeared (with stable ids) in SCOP 1.55
  
• Family a.4.5.14: Forkhead DNA-binding domain appears in SCOPe 2.05
  
• Family a.4.5.14: Forkhead DNA-binding domain appears in SCOPe 2.07
  
• Family a.4.5.14: Forkhead DNA-binding domain appears in the current release, SCOPe 2.08