Lineage for Family a.1.1.2: Globins

  1. Root: SCOPe 2.06
  2. 1976409Class a: All alpha proteins [46456] (289 folds)
  3. 1976410Fold a.1: Globin-like [46457] (2 superfamilies)
    core: 6 helices; folded leaf, partly opened
  4. 1976411Superfamily a.1.1: Globin-like [46458] (5 families) (S)
  5. 1976495Family a.1.1.2: Globins [46463] (27 protein domains)
    Heme-binding protein

Protein Domains:

  1. 1976496Ascaris hemoglobin, domain 1 [46520] (1 species)
  2. 1976499Bacterial dimeric hemoglobin [46526] (1 species)
  3. 1976513Chimeric hemoglobin beta-alpha [46516] (1 species)
  4. 1976519Cytoglobin [109626] (1 species)
  5. 1976535Dehaloperoxidase [46530] (1 species)
  6. 1976599Erythrocruorin [46479] (1 species)
  7. 1976605Extracellular dodecameric hemoglobin (erythrocruorin), subunit D1 [116758] (1 species)
  8. 1976613Extracellular dodecameric hemoglobin (erythrocruorin), subunit II (globin B) [116754] (1 species)
  9. 1976621Extracellular dodecameric hemoglobin (erythrocruorin), subunit III (globin C) [116756] (1 species)
  10. 1976629Extracellular dodecameric hemoglobin (erythrocruorin), subunit IV (globin A) [116752] (1 species)
  11. 1976637Flavohemoglobin, N-terminal domain [46528] (2 species)
    1. 1976638Species Alcaligenes eutrophus [TaxId:106590] [46529] (1 PDB entry)
    2. 1976641Species Escherichia coli [TaxId:562] [74663] (1 PDB entry)
  12. 1976643Glycera globin [46467] (1 species)
  13. 1976653Hagfish hemoglobin [68941] (1 species)
  14. 1976661Heme-based aerotactic transducer HemAT, sensor domain [100980] (1 species)
  15. 1976667Hemoglobin [46522] (1 species)
  16. 1976671Hemoglobin I [46464] (2 species)
    1. 1976672Species Ark clam (Scapharca inaequivalvis) [TaxId:6561] [46465] (37 PDB entries)
    2. 1976761Species Clam (Lucina pectinata) [TaxId:244486] [46466] (4 PDB entries)
  17. 1976766Hemoglobin, alpha-chain [46486] (24 species)
    1. 1976767Species Aldabra giant tortoise (Geochelone gigantea) [TaxId:167804] [100976] (3 PDB entries)
      Uniprot P83134
    2. 1976771Species Antarctic fish (Trematomus newnesi) [TaxId:35730] [46497] (7 PDB entries)
    3. 1976783Species Bar-headed goose (Anser indicus) [TaxId:8846] [46493] (4 PDB entries)
    4. 1976791Species Bluefin tuna (Thunnus thynnus) [TaxId:8237] [109623] (3 PDB entries)
      Uniprot Q8AYM0
    5. 1976798Species Cartilaginous fish akaei (Dasyatis akajei) [TaxId:31902] [46496] (2 PDB entries)
    6. 1976801Species Chicken (Gallus gallus) [TaxId:9031] [46492] (1 PDB entry)
    7. 1976804Species Cow (Bos taurus) [TaxId:9913] [46490] (11 PDB entries)
    8. 1976827Species Deer (Odocoileus virginianus) [TaxId:9874] [46489] (1 PDB entry)
    9. 1976830Species Dog (Canis familiaris) [TaxId:9615] [189534] (3 PDB entries)
    10. 1976835Species Donkey (Equus asinus) [TaxId:9793] [158217] (1 PDB entry)
      Uniprot P01959 1-141
      beta-chain sequences of donkey and horse hemoglobins are identical
    11. 1976837Species Dusicyon thous [TaxId:9620] [186966] (1 PDB entry)
    12. 1976841Species Emerald rockcod (Pagothenia bernacchii) [TaxId:40690] [46495] (12 PDB entries)
    13. 1976861Species Fish (Leiostomus xanthurus) [TaxId:59837] [46498] (1 PDB entry)
    14. 1976863Species Graylag goose (Anser anser) [TaxId:8843] [68938] (1 PDB entry)
    15. 1976866Species Horse (Equus caballus) [TaxId:9796] [46488] (17 PDB entries)
    16. 1976889Species Houndshark (Mustelus griseus) [TaxId:89020] [46499] (2 PDB entries)
    17. 1976894Species Human (Homo sapiens) [TaxId:9606] [46487] (253 PDB entries)
      Uniprot P69905 P01922 P01934 P01935
    18. 1977414Species Human (Homo sapiens), zeta isoform [TaxId:9606] [68937] (2 PDB entries)
    19. 1977420Species Maned wolf (Chrysocyon brachyurus) [TaxId:68728] [63440] (1 PDB entry)
    20. 1977423Species Ochotona princeps [TaxId:9978] [326613] (1 PDB entry)
    21. 1977425Species Peromyscus maniculatus [TaxId:10042] [224840] (1 PDB entry)
    22. 1977427Species Pig (Sus scrofa) [TaxId:9823] [46491] (3 PDB entries)
    23. 1977436Species Rainbow trout (Oncorhynchus mykiss) [TaxId:8022] [46494] (2 PDB entries)
    24. 1977440Species Yellow perch (Perca flavescens) [TaxId:8167] [116749] (1 PDB entry)
      Uniprot P83270; 78% sequence identity
  18. 1977443Hemoglobin, beta-chain [46500] (25 species)
    1. 1977444Species Aldabra giant tortoise (Geochelone gigantea) [TaxId:167804] [100977] (3 PDB entries)
      Uniprot P83133
    2. 1977448Species Antarctic fish (Trematomus newnesi) [TaxId:35730] [46513] (7 PDB entries)
    3. 1977460Species Bar-headed goose (Anser indicus) [TaxId:8846] [46509] (4 PDB entries)
    4. 1977468Species Bluefin tuna (Thunnus thynnus) [TaxId:8237] [109624] (3 PDB entries)
      Uniprot Q8AYM1
    5. 1977475Species Canis lupus [TaxId:9615] [311319] (1 PDB entry)
    6. 1977477Species Cartilaginous fish akaei (Dasyatis akajei) [TaxId:31902] [46512] (2 PDB entries)
    7. 1977480Species Chicken (Gallus gallus) [TaxId:9031] [46508] (1 PDB entry)
    8. 1977483Species Cow (Bos taurus) [TaxId:9913] [46506] (11 PDB entries)
    9. 1977506Species Deer (Odocoileus virginianus) [TaxId:9874] [46505] (1 PDB entry)
    10. 1977509Species Dog (Canis familiaris) [TaxId:9615] [158218] (3 PDB entries)
    11. 1977515Species Donkey (Equus asinus) [TaxId:9793] [158216] (1 PDB entry)
      beta-chain sequences of donkey and horse hemoglobins are identical
    12. 1977517Species Emerald rockcod (Pagothenia bernacchii) [TaxId:40690] [46511] (12 PDB entries)
    13. 1977537Species Fish (Leiostomus xanthurus) [TaxId:59837] [46514] (1 PDB entry)
    14. 1977539Species Graylag goose (Anser anser) [TaxId:8843] [68940] (1 PDB entry)
    15. 1977542Species Horse (Equus caballus) [TaxId:9796] [46504] (17 PDB entries)
    16. 1977565Species Houndshark (Mustelus griseus) [TaxId:89020] [46515] (2 PDB entries)
    17. 1977570Species Human (Homo sapiens) [TaxId:9606] [46501] (245 PDB entries)
      Uniprot P68871
    18. 1978075Species Human (Homo sapiens), delta-chain [TaxId:9606] [116750] (2 PDB entries)
      Uniprot P02042
    19. 1978080Species Human (Homo sapiens), embryonic gower II [TaxId:9606] [46503] (1 PDB entry)
    20. 1978083Species Human fetus (Homo sapiens), gamma-chain [TaxId:9606] [46502] (3 PDB entries)
    21. 1978090Species Maned wolf (Chrysocyon brachyurus) [TaxId:68728] [63441] (1 PDB entry)
    22. 1978093Species Mouse (Mus musculus) [TaxId:10090] [68939] (1 PDB entry)
    23. 1978096Species Pig (Sus scrofa) [TaxId:9823] [46507] (3 PDB entries)
    24. 1978105Species Rainbow trout (Oncorhynchus mykiss) [TaxId:8022] [46510] (2 PDB entries)
    25. 1978109Species Yellow perch (Perca flavescens) [TaxId:8167] [116751] (4 PDB entries)
      Uniprot P83273; 86% sequence identity
  19. 1978118Hemoglobin, different isoforms [46524] (1 species)
  20. 1978122Hypothetical protein PA3967 [109628] (1 species)
  21. 1978125Lamprey globin [46518] (2 species)
    1. 1978126Species Lamprey (Lampetra fluviatilis) [TaxId:7748] [88966] (1 PDB entry)
    2. 1978139Species Sea lamprey (Petromyzon marinus) [TaxId:7757] [46519] (4 PDB entries)
  22. 1978165Leghemoglobin [46481] (2 species)
    1. 1978166Species Soybean (Glycine max), isoform A [TaxId:3847] [46483] (2 PDB entries)
    2. 1978171Species Yellow lupine (Lupinus luteus) [TaxId:3873] [46482] (17 PDB entries)
  23. 1978189Myoglobin [46469] (10 species)
    1. 1978190Species Asian elephant (Elephas maximus) [TaxId:9783] [46476] (1 PDB entry)
    2. 1978192Species Common seal (Phoca vitulina) [TaxId:9720] [46472] (1 PDB entry)
    3. 1978194Species Horse (Equus caballus) [TaxId:9796] [46474] (84 PDB entries)
    4. 1978284Species Human (Homo sapiens) [TaxId:9606] [46475] (1 PDB entry)
    5. 1978286Species Kogia sima [TaxId:9752] [342029] (1 PDB entry)
    6. 1978289Species Loggerhead sea turtle (Caretta caretta) [TaxId:8467] [46477] (2 PDB entries)
    7. 1978292Species Pig (Sus scrofa) [TaxId:9823] [46473] (17 PDB entries)
    8. 1978326Species Slug sea hare (Aplysia limacina) [TaxId:6502] [46471] (7 PDB entries)
    9. 1978334Species Sperm whale (Physeter catodon) [TaxId:9755] [46470] (267 PDB entries)
      Uniprot P02185
    10. 1978603Species Yellowfin tuna (Thunnus albacares) [TaxId:8236] [46478] (1 PDB entry)
  24. 1978605Neuroglobin [100978] (2 species)
    1. 1978606Species Human (Homo sapiens) [TaxId:9606] [100979] (2 PDB entries)
    2. 1978613Species Mouse (Mus musculus) [TaxId:10090] [109625] (30 PDB entries)
      Uniprot Q9ER97
  25. 1978644Non-symbiotic plant hemoglobin [46484] (1 species)
  26. 1978652Trematode hemoglobin/myoglobin [63438] (1 species)
  27. 1978657automated matches [190359] (42 species)
    not a true protein
    1. 1978658Species Acipenser persicus [TaxId:61968] [333390] (1 PDB entry)
    2. 1978660Species Amphitrite ornata [TaxId:129555] [189339] (9 PDB entries)
    3. 1978679Species Ark clam (Scapharca inaequivalvis) [TaxId:6561] [187427] (32 PDB entries)
    4. 1978752Species Barley (Hordeum vulgare) [TaxId:4513] [187359] (1 PDB entry)
    5. 1978761Species Brycon cephalus [TaxId:126311] [188621] (1 PDB entry)
    6. 1978766Species Buffalo (Bubalus bubalis) [TaxId:89462] [188864] (1 PDB entry)
    7. 1978771Species Camel (Camelus dromedarius) [TaxId:9838] [189249] (1 PDB entry)
    8. 1978776Species Cat (Felis catus) [TaxId:9685] [188888] (4 PDB entries)
    9. 1978801Species Coturnix japonica [TaxId:93934] [189557] (1 PDB entry)
    10. 1978806Species Domestic pigeon (Columba livia) [TaxId:8932] [188616] (2 PDB entries)
    11. 1978819Species Dromaius novaehollandiae [TaxId:8790] [258618] (1 PDB entry)
    12. 1978824Species Duck (Anas platyrhynchos) [TaxId:8839] [189063] (1 PDB entry)
    13. 1978827Species Dusicyon thous [TaxId:9620] [187446] (1 PDB entry)
    14. 1978829Species Eleginops maclovinus [TaxId:56733] [193401] (1 PDB entry)
    15. 1978834Species Escherichia coli [TaxId:562] [196657] (1 PDB entry)
    16. 1978837Species Glossoscolex paulistus [TaxId:1046353] [273742] (1 PDB entry)
    17. 1978839Species Goat (Capra hircus) [TaxId:9925] [188635] (3 PDB entries)
    18. 1978856Species Guinea pig (Cavia porcellus) [TaxId:10141] [189281] (2 PDB entries)
    19. 1978861Species Helogale parvula [TaxId:210647] [277372] (2 PDB entries)
    20. 1978868Species Human (Homo sapiens) [TaxId:9606] [188371] (6 PDB entries)
    21. 1978886Species Isurus oxyrinchus [TaxId:57983] [189618] (1 PDB entry)
    22. 1978891Species Lepus europaeus [TaxId:9983] [189630] (1 PDB entry)
    23. 1978896Species Maize (Zea mays) [TaxId:76912] [188014] (1 PDB entry)
    24. 1978901Species Mammuthus primigenius [TaxId:37349] [194337] (3 PDB entries)
    25. 1978910Species Mouse (Mus musculus) [TaxId:10090] [187190] (2 PDB entries)
    26. 1978916Species Norway rat (Rattus norvegicus) [TaxId:10116] [188924] (2 PDB entries)
    27. 1978923Species Ochotona princeps [TaxId:9978] [326616] (1 PDB entry)
    28. 1978925Species Parasponia andersonii [TaxId:3476] [193708] (1 PDB entry)
    29. 1978928Species Peromyscus maniculatus [TaxId:10042] [196779] (2 PDB entries)
    30. 1978938Species Podocnemis unifilis [TaxId:227871] [189922] (2 PDB entries)
    31. 1978943Species Psittacula krameri [TaxId:9228] [255724] (1 PDB entry)
    32. 1978946Species Pteropus giganteus [TaxId:143291] [188768] (1 PDB entry)
    33. 1978949Species Rabbit (Oryctolagus cuniculus) [TaxId:9986] [188592] (1 PDB entry)
    34. 1978954Species Rainbow trout (Oncorhynchus mykiss) [TaxId:8022] [188309] (2 PDB entries)
    35. 1978963Species Sheep (Ovis aries) [TaxId:9940] [188522] (1 PDB entry)
    36. 1978968Species Sperm whale (Physeter catodon) [TaxId:9755] [188226] (4 PDB entries)
    37. 1978973Species Struthio camelus [TaxId:8801] [188835] (1 PDB entry)
    38. 1978978Species Thunnus atlanticus [TaxId:48168] [187921] (8 PDB entries)
    39. 1978987Species Thunnus orientalis [TaxId:8238] [187933] (1 PDB entry)
    40. 1978989Species Trema tomentosa [TaxId:3480] [196352] (1 PDB entry)
    41. 1978992Species Turkey (Meleagris gallopavo) [TaxId:9103] [189160] (2 PDB entries)
    42. 1979001Species Yellow perch (Perca flavescens) [TaxId:8167] [188574] (3 PDB entries)

More info for Family a.1.1.2: Globins

Timeline for Family a.1.1.2: Globins: