Lineage for Family a.1.1.2: Globins

  1. Root: SCOPe 2.07
  2. 2299346Class a: All alpha proteins [46456] (289 folds)
  3. 2299347Fold a.1: Globin-like [46457] (2 superfamilies)
    core: 6 helices; folded leaf, partly opened
  4. 2299348Superfamily a.1.1: Globin-like [46458] (5 families) (S)
  5. 2299432Family a.1.1.2: Globins [46463] (27 protein domains)
    Heme-binding protein

Protein Domains:

  1. 2299433Ascaris hemoglobin, domain 1 [46520] (1 species)
  2. 2299436Bacterial dimeric hemoglobin [46526] (1 species)
  3. 2299450Chimeric hemoglobin beta-alpha [46516] (1 species)
  4. 2299456Cytoglobin [109626] (1 species)
  5. 2299472Dehaloperoxidase [46530] (1 species)
  6. 2299536Erythrocruorin [46479] (1 species)
  7. 2299542Extracellular dodecameric hemoglobin (erythrocruorin), subunit D1 [116758] (1 species)
  8. 2299550Extracellular dodecameric hemoglobin (erythrocruorin), subunit II (globin B) [116754] (1 species)
  9. 2299558Extracellular dodecameric hemoglobin (erythrocruorin), subunit III (globin C) [116756] (1 species)
  10. 2299566Extracellular dodecameric hemoglobin (erythrocruorin), subunit IV (globin A) [116752] (1 species)
  11. 2299574Flavohemoglobin, N-terminal domain [46528] (2 species)
    1. 2299575Species Alcaligenes eutrophus [TaxId:106590] [46529] (1 PDB entry)
    2. 2299578Species Escherichia coli [TaxId:562] [74663] (1 PDB entry)
  12. 2299580Glycera globin [46467] (1 species)
  13. 2299590Hagfish hemoglobin [68941] (1 species)
  14. 2299598Heme-based aerotactic transducer HemAT, sensor domain [100980] (1 species)
  15. 2299604Hemoglobin [46522] (1 species)
  16. 2299608Hemoglobin I [46464] (2 species)
    1. 2299609Species Ark clam (Scapharca inaequivalvis) [TaxId:6561] [46465] (37 PDB entries)
    2. 2299698Species Clam (Lucina pectinata) [TaxId:244486] [46466] (4 PDB entries)
  17. 2299703Hemoglobin, alpha-chain [46486] (24 species)
    1. 2299704Species Aldabra giant tortoise (Geochelone gigantea) [TaxId:167804] [100976] (3 PDB entries)
      Uniprot P83134
    2. 2299708Species Antarctic fish (Trematomus newnesi) [TaxId:35730] [46497] (7 PDB entries)
    3. 2299720Species Bar-headed goose (Anser indicus) [TaxId:8846] [46493] (4 PDB entries)
    4. 2299728Species Bluefin tuna (Thunnus thynnus) [TaxId:8237] [109623] (3 PDB entries)
      Uniprot Q8AYM0
    5. 2299735Species Cartilaginous fish akaei (Dasyatis akajei) [TaxId:31902] [46496] (2 PDB entries)
    6. 2299738Species Chicken (Gallus gallus) [TaxId:9031] [46492] (1 PDB entry)
    7. 2299741Species Cow (Bos taurus) [TaxId:9913] [46490] (11 PDB entries)
    8. 2299764Species Deer (Odocoileus virginianus) [TaxId:9874] [46489] (1 PDB entry)
    9. 2299767Species Dog (Canis familiaris) [TaxId:9615] [189534] (3 PDB entries)
    10. 2299772Species Donkey (Equus asinus) [TaxId:9793] [158217] (1 PDB entry)
      Uniprot P01959 1-141
      beta-chain sequences of donkey and horse hemoglobins are identical
    11. 2299774Species Dusicyon thous [TaxId:9620] [186966] (1 PDB entry)
    12. 2299778Species Emerald rockcod (Pagothenia bernacchii) [TaxId:40690] [46495] (12 PDB entries)
    13. 2299798Species Fish (Leiostomus xanthurus) [TaxId:59837] [46498] (1 PDB entry)
    14. 2299800Species Graylag goose (Anser anser) [TaxId:8843] [68938] (1 PDB entry)
    15. 2299803Species Horse (Equus caballus) [TaxId:9796] [46488] (17 PDB entries)
    16. 2299826Species Houndshark (Mustelus griseus) [TaxId:89020] [46499] (2 PDB entries)
    17. 2299831Species Human (Homo sapiens) [TaxId:9606] [46487] (256 PDB entries)
      Uniprot P69905 P01922 P01934 P01935
    18. 2300350Species Human (Homo sapiens), zeta isoform [TaxId:9606] [68937] (2 PDB entries)
    19. 2300356Species Maned wolf (Chrysocyon brachyurus) [TaxId:68728] [63440] (1 PDB entry)
    20. 2300359Species Ochotona princeps [TaxId:9978] [326613] (1 PDB entry)
    21. 2300361Species Peromyscus maniculatus [TaxId:10042] [224840] (1 PDB entry)
    22. 2300363Species Pig (Sus scrofa) [TaxId:9823] [46491] (3 PDB entries)
    23. 2300372Species Rainbow trout (Oncorhynchus mykiss) [TaxId:8022] [46494] (2 PDB entries)
    24. 2300376Species Yellow perch (Perca flavescens) [TaxId:8167] [116749] (1 PDB entry)
      Uniprot P83270; 78% sequence identity
  18. 2300379Hemoglobin, beta-chain [46500] (26 species)
    1. 2300380Species Aldabra giant tortoise (Geochelone gigantea) [TaxId:167804] [100977] (3 PDB entries)
      Uniprot P83133
    2. 2300384Species Antarctic fish (Trematomus newnesi) [TaxId:35730] [46513] (7 PDB entries)
    3. 2300396Species Bar-headed goose (Anser indicus) [TaxId:8846] [46509] (4 PDB entries)
    4. 2300404Species Bluefin tuna (Thunnus thynnus) [TaxId:8237] [109624] (3 PDB entries)
      Uniprot Q8AYM1
    5. 2300411Species Canis lupus [TaxId:9615] [311319] (1 PDB entry)
    6. 2300413Species Cartilaginous fish akaei (Dasyatis akajei) [TaxId:31902] [46512] (2 PDB entries)
    7. 2300416Species Chicken (Gallus gallus) [TaxId:9031] [46508] (1 PDB entry)
    8. 2300419Species Cow (Bos taurus) [TaxId:9913] [46506] (11 PDB entries)
    9. 2300442Species Deer (Odocoileus virginianus) [TaxId:9874] [46505] (1 PDB entry)
    10. 2300445Species Dog (Canis familiaris) [TaxId:9615] [158218] (3 PDB entries)
    11. 2300451Species Donkey (Equus asinus) [TaxId:9793] [158216] (1 PDB entry)
      beta-chain sequences of donkey and horse hemoglobins are identical
    12. 2300453Species Emerald rockcod (Pagothenia bernacchii) [TaxId:40690] [46511] (12 PDB entries)
    13. 2300473Species Fish (Leiostomus xanthurus) [TaxId:59837] [46514] (1 PDB entry)
    14. 2300475Species Graylag goose (Anser anser) [TaxId:8843] [68940] (1 PDB entry)
    15. 2300478Species Horse (Equus caballus) [TaxId:9796] [46504] (17 PDB entries)
    16. 2300501Species Houndshark (Mustelus griseus) [TaxId:89020] [46515] (2 PDB entries)
    17. 2300506Species Human (Homo sapiens) [TaxId:9606] [46501] (252 PDB entries)
      Uniprot P68871
    18. 2301010Species Human (Homo sapiens), delta-chain [TaxId:9606] [116750] (2 PDB entries)
      Uniprot P02042
    19. 2301015Species Human (Homo sapiens), embryonic gower II [TaxId:9606] [46503] (1 PDB entry)
    20. 2301018Species Human fetus (Homo sapiens), gamma-chain [TaxId:9606] [46502] (3 PDB entries)
    21. 2301025Species Maned wolf (Chrysocyon brachyurus) [TaxId:68728] [63441] (1 PDB entry)
    22. 2301028Species Mouse (Mus musculus) [TaxId:10090] [68939] (1 PDB entry)
    23. 2301031Species Ochotona princeps [TaxId:9978] [346154] (1 PDB entry)
    24. 2301033Species Pig (Sus scrofa) [TaxId:9823] [46507] (3 PDB entries)
    25. 2301042Species Rainbow trout (Oncorhynchus mykiss) [TaxId:8022] [46510] (2 PDB entries)
    26. 2301046Species Yellow perch (Perca flavescens) [TaxId:8167] [116751] (4 PDB entries)
      Uniprot P83273; 86% sequence identity
  19. 2301055Hemoglobin, different isoforms [46524] (1 species)
  20. 2301059Hypothetical protein PA3967 [109628] (1 species)
  21. 2301062Lamprey globin [46518] (2 species)
    1. 2301063Species Lamprey (Lampetra fluviatilis) [TaxId:7748] [88966] (1 PDB entry)
    2. 2301076Species Sea lamprey (Petromyzon marinus) [TaxId:7757] [46519] (4 PDB entries)
  22. 2301102Leghemoglobin [46481] (2 species)
    1. 2301103Species Soybean (Glycine max), isoform A [TaxId:3847] [46483] (2 PDB entries)
    2. 2301108Species Yellow lupine (Lupinus luteus) [TaxId:3873] [46482] (17 PDB entries)
  23. 2301126Myoglobin [46469] (10 species)
    1. 2301127Species Asian elephant (Elephas maximus) [TaxId:9783] [46476] (1 PDB entry)
    2. 2301129Species Common seal (Phoca vitulina) [TaxId:9720] [46472] (1 PDB entry)
    3. 2301131Species Horse (Equus caballus) [TaxId:9796] [46474] (84 PDB entries)
    4. 2301221Species Human (Homo sapiens) [TaxId:9606] [46475] (1 PDB entry)
    5. 2301223Species Kogia sima [TaxId:9752] [342029] (1 PDB entry)
    6. 2301226Species Loggerhead sea turtle (Caretta caretta) [TaxId:8467] [46477] (2 PDB entries)
    7. 2301229Species Pig (Sus scrofa) [TaxId:9823] [46473] (17 PDB entries)
    8. 2301263Species Slug sea hare (Aplysia limacina) [TaxId:6502] [46471] (7 PDB entries)
    9. 2301271Species Sperm whale (Physeter catodon) [TaxId:9755] [46470] (294 PDB entries)
      Uniprot P02185
    10. 2301539Species Yellowfin tuna (Thunnus albacares) [TaxId:8236] [46478] (1 PDB entry)
  24. 2301541Neuroglobin [100978] (2 species)
    1. 2301542Species Human (Homo sapiens) [TaxId:9606] [100979] (2 PDB entries)
    2. 2301549Species Mouse (Mus musculus) [TaxId:10090] [109625] (30 PDB entries)
      Uniprot Q9ER97
  25. 2301580Non-symbiotic plant hemoglobin [46484] (1 species)
  26. 2301588Trematode hemoglobin/myoglobin [63438] (1 species)
  27. 2301593automated matches [190359] (42 species)
    not a true protein
    1. 2301594Species Acipenser persicus [TaxId:61968] [333390] (1 PDB entry)
    2. 2301596Species Amphitrite ornata [TaxId:129555] [189339] (14 PDB entries)
    3. 2301615Species Ark clam (Scapharca inaequivalvis) [TaxId:6561] [187427] (32 PDB entries)
    4. 2301688Species Barley (Hordeum vulgare) [TaxId:4513] [187359] (1 PDB entry)
    5. 2301697Species Brycon cephalus [TaxId:126311] [188621] (1 PDB entry)
    6. 2301702Species Buffalo (Bubalus bubalis) [TaxId:89462] [188864] (1 PDB entry)
    7. 2301707Species Camel (Camelus dromedarius) [TaxId:9838] [189249] (1 PDB entry)
    8. 2301712Species Cat (Felis catus) [TaxId:9685] [188888] (4 PDB entries)
    9. 2301737Species Coturnix japonica [TaxId:93934] [189557] (1 PDB entry)
    10. 2301742Species Domestic pigeon (Columba livia) [TaxId:8932] [188616] (2 PDB entries)
    11. 2301755Species Dromaius novaehollandiae [TaxId:8790] [258618] (1 PDB entry)
    12. 2301760Species Duck (Anas platyrhynchos) [TaxId:8839] [189063] (1 PDB entry)
    13. 2301763Species Dusicyon thous [TaxId:9620] [187446] (1 PDB entry)
    14. 2301765Species Eleginops maclovinus [TaxId:56733] [193401] (1 PDB entry)
    15. 2301770Species Escherichia coli [TaxId:562] [196657] (1 PDB entry)
    16. 2301773Species Glossoscolex paulistus [TaxId:1046353] [273742] (1 PDB entry)
    17. 2301775Species Goat (Capra hircus) [TaxId:9925] [188635] (3 PDB entries)
    18. 2301792Species Guinea pig (Cavia porcellus) [TaxId:10141] [189281] (2 PDB entries)
    19. 2301797Species Helogale parvula [TaxId:210647] [277372] (2 PDB entries)
    20. 2301804Species Human (Homo sapiens) [TaxId:9606] [188371] (9 PDB entries)
    21. 2301822Species Isurus oxyrinchus [TaxId:57983] [189618] (1 PDB entry)
    22. 2301827Species Lepus europaeus [TaxId:9983] [189630] (1 PDB entry)
    23. 2301832Species Maize (Zea mays) [TaxId:76912] [188014] (1 PDB entry)
    24. 2301837Species Mammuthus primigenius [TaxId:37349] [194337] (3 PDB entries)
    25. 2301846Species Mouse (Mus musculus) [TaxId:10090] [187190] (2 PDB entries)
    26. 2301852Species Norway rat (Rattus norvegicus) [TaxId:10116] [188924] (2 PDB entries)
    27. 2301859Species Parasponia andersonii [TaxId:3476] [193708] (1 PDB entry)
    28. 2301862Species Peromyscus maniculatus [TaxId:10042] [196779] (2 PDB entries)
    29. 2301872Species Podocnemis unifilis [TaxId:227871] [189922] (2 PDB entries)
    30. 2301877Species Psittacula krameri [TaxId:9228] [255724] (1 PDB entry)
    31. 2301880Species Pteropus giganteus [TaxId:143291] [188768] (1 PDB entry)
    32. 2301883Species Rabbit (Oryctolagus cuniculus) [TaxId:9986] [188592] (1 PDB entry)
    33. 2301888Species Rainbow trout (Oncorhynchus mykiss) [TaxId:8022] [188309] (2 PDB entries)
    34. 2301897Species Sheep (Ovis aries) [TaxId:9940] [188522] (1 PDB entry)
    35. 2301902Species Sperm whale (Physeter catodon) [TaxId:9755] [188226] (4 PDB entries)
    36. 2301907Species Struthio camelus [TaxId:8801] [188835] (1 PDB entry)
    37. 2301912Species Thunnus atlanticus [TaxId:48168] [187921] (8 PDB entries)
    38. 2301921Species Thunnus orientalis [TaxId:8238] [187933] (1 PDB entry)
    39. 2301923Species Trema tomentosa [TaxId:3480] [196352] (1 PDB entry)
    40. 2301926Species Turkey (Meleagris gallopavo) [TaxId:9103] [189160] (2 PDB entries)
    41. 2301935Species Yellow perch (Perca flavescens) [TaxId:8167] [188574] (3 PDB entries)
    42. 3048888Species Equus caballus [TaxId:9796] [348950] (1 PDB entry)

More info for Family a.1.1.2: Globins

Timeline for Family a.1.1.2: Globins: