SCOPe 2.05: Domain d1es7c_: 1es7 C:

Lineage for d1es7c_ (1es7 C:)

1. Root: SCOPe 2.05

2. Class g: Small proteins [56992] (92 folds)

3. Fold g.17: Cystine-knot cytokines [57500] (1 superfamily)
   disulfide-rich fold; common core is all-beta

4. Superfamily g.17.1: Cystine-knot cytokines [57501] (8 families)

5. Family g.17.1.2: Transforming growth factor (TGF)-beta [57507] (8 proteins)

6. Protein Bone morphogenetic protein-2 (BMP-2) [57516] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [57517] (13 PDB entries)

8. Domain d1es7c_: 1es7 C: [44787]
   Other proteins in same PDB: d1es7b_, d1es7d_

Details for d1es7c_

PDB Entry: 1es7, 2.9 Å

PDB Description: complex between bmp-2 and two bmp receptor ia ectodomains

PDB Compounds: (C:) bone morphogenetic protein-2

SCOPe Domain Sequences for d1es7c_:

Sequence; same for both SEQRES and ATOM records:

>d1es7c_ g.17.1.2 (C:) Bone morphogenetic protein-2 (BMP-2) {Human (Homo sapiens) [TaxId: 9606]}
kssckrhplyvdfsdvgwndwivappgyhafychgecpfpladhlnstnhaivqtlvnsv
nskipkaccvptelsaismlyldenekvvlknyqdmvvegcgcr

Timeline for d1es7c_:

• d1es7c_ first appeared (with stable ids) in SCOP 1.55
  
• d1es7c_ appears in SCOPe 2.04
  
• d1es7c_ appears in SCOPe 2.06
  
• d1es7c_ appears in the current release, SCOPe 2.08