SCOPe 2.05: Domain d1tgja_: 1tgj A:

Lineage for d1tgja_ (1tgj A:)

1. Root: SCOPe 2.05

2. Class g: Small proteins [56992] (92 folds)

3. Fold g.17: Cystine-knot cytokines [57500] (1 superfamily)
   disulfide-rich fold; common core is all-beta

4. Superfamily g.17.1: Cystine-knot cytokines [57501] (8 families)

5. Family g.17.1.2: Transforming growth factor (TGF)-beta [57507] (8 proteins)

6. Protein TGF-beta3 [57508] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [57509] (5 PDB entries)

8. Domain d1tgja_: 1tgj A: [44775]
   complexed with dio

Details for d1tgja_

PDB Entry: 1tgj, 2 Å

PDB Description: human transforming growth factor-beta 3, crystallized from dioxane

PDB Compounds: (A:) transforming growth factor-beta 3

SCOPe Domain Sequences for d1tgja_:

Sequence; same for both SEQRES and ATOM records:

>d1tgja_ g.17.1.2 (A:) TGF-beta3 {Human (Homo sapiens) [TaxId: 9606]}
aldtnycfrnleenccvrplyidfrqdlgwkwvhepkgyyanfcsgpcpylrsadtthst
vlglyntlnpeasaspccvpqdlepltilyyvgrtpkveqlsnmvvksckcs

Timeline for d1tgja_:

• d1tgja_ first appeared (with stable ids) in SCOP 1.55, called d1tgj__
  
• d1tgja_ appears in SCOPe 2.04
  
• d1tgja_ appears in SCOPe 2.06
  
• d1tgja_ appears in the current release, SCOPe 2.08