SCOPe 2.04: Domain d1fltw_: 1flt W:

Lineage for d1fltw_ (1flt W:)

1. Root: SCOPe 2.04

2. Class g: Small proteins [56992] (91 folds)

3. Fold g.17: Cystine-knot cytokines [57500] (1 superfamily)
   disulfide-rich fold; common core is all-beta

4. Superfamily g.17.1: Cystine-knot cytokines [57501] (8 families)

5. Family g.17.1.1: Platelet-derived growth factor-like [57502] (4 proteins)

6. Protein Vascular endothelial growth factor, VEGF [57505] (3 species)

7. Species Human (Homo sapiens) [TaxId:9606] [57506] (16 PDB entries)
   Uniprot P15692 40-133

8. Domain d1fltw_: 1flt W: [44752]
   Other proteins in same PDB: d1fltx_, d1flty_

Details for d1fltw_

PDB Entry: 1flt, 1.7 Å

PDB Description: vegf in complex with domain 2 of the flt-1 receptor

PDB Compounds: (W:) vascular endothelial growth factor

SCOPe Domain Sequences for d1fltw_:

Sequence; same for both SEQRES and ATOM records:

>d1fltw_ g.17.1.1 (W:) Vascular endothelial growth factor, VEGF {Human (Homo sapiens) [TaxId: 9606]}
hevvkfmdvyqrsychpietlvdifqeypdeieyifkpscvplmrcggccndeglecvpt
eesnitmqimrikphqgqhigemsflqhnkcecrpkkd

Timeline for d1fltw_:

• d1fltw_ first appeared (with stable ids) in SCOP 1.55
  
• d1fltw_ appears in SCOPe 2.03
  
• d1fltw_ appears in SCOPe 2.05
  
• d1fltw_ appears in the current release, SCOPe 2.08