SCOP 1.69: Domain d1skz_2: 1skz 59-110

Lineage for d1skz_2 (1skz 59-110)

1. Root: SCOP 1.69

2. Class g: Small proteins [56992] (75 folds)

3. Fold g.3: Knottins (small inhibitors, toxins, lectins) [57015] (19 superfamilies)
   disulfide-bound fold; contains beta-hairpin with two adjacent disulfides

4. Superfamily g.3.15: Leech antihemostatic proteins [57262] (2 families)

5. Family g.3.15.1: Huristasin-like [57263] (3 proteins)

6. Protein Factor Xa inhibitor antistasin [57268] (1 species)
   duplication: consists of two similar domain

7. Species Mexican leech (Haementeria officinalis) [TaxId:6410] [57269] (1 PDB entry)

8. Domain d1skz_2: 1skz 59-110 [44367]

Details for d1skz_2

PDB Entry: 1skz, 1.9 Å

PDB Description: protease inhibitor

SCOP Domain Sequences for d1skz_2:

Sequence; same for both SEQRES and ATOM records:

>d1skz_2 g.3.15.1 (59-110) Factor Xa inhibitor antistasin {Mexican leech (Haementeria officinalis)}
katcdisecpegmmcsrltnkcdckidincrktcpnglkrdklgceycecrp

Timeline for d1skz_2:

• d1skz_2 first appeared (with stable ids) in SCOP 1.55
  
• d1skz_2 appears in SCOP 1.67
  
• d1skz_2 appears in SCOP 1.71
  
• d1skz_2 appears in the current release, SCOPe 2.08, called d1skza2