SCOP 1.75: Domain d1pgea2: 1pge A:33-73

Lineage for d1pgea2 (1pge A:33-73)

1. Root: SCOP 1.75

2. Class g: Small proteins [56992] (90 folds)

3. Fold g.3: Knottins (small inhibitors, toxins, lectins) [57015] (19 superfamilies)
   disulfide-bound fold; contains beta-hairpin with two adjacent disulfides

4. Superfamily g.3.11: EGF/Laminin [57196] (7 families)

5. Family g.3.11.1: EGF-type module [57197] (22 proteins)

6. Protein Prostaglandin H2 synthase-1, EGF-like module [57210] (2 species)
   the rest of protein is heme-linked peroxidase, all-alpha fold

7. Species Sheep (Ovis aries) [TaxId:9940] [57211] (20 PDB entries)
   Uniprot P05979 32-584

8. Domain d1pgea2: 1pge A:33-73 [44250]
   Other proteins in same PDB: d1pgea1, d1pgeb1

Details for d1pgea2

PDB Entry: 1pge, 3.5 Å

PDB Description: prostaglandin h2 synthase-1 complexed with p-(2'-iodo-5'-thenoyl) hydrotropic acid (iodosuprofen)

PDB Compounds: (A:) prostaglandin h2 synthase-1

SCOP Domain Sequences for d1pgea2:

Sequence; same for both SEQRES and ATOM records:

>d1pgea2 g.3.11.1 (A:33-73) Prostaglandin H2 synthase-1, EGF-like module {Sheep (Ovis aries) [TaxId: 9940]}
vnpccyypcqhqgicvrfgldryqcdctrtgysgpnctipe

Timeline for d1pgea2:

• d1pgea2 first appeared (with stable ids) in SCOP 1.55
  
• d1pgea2 appears in SCOP 1.73
  
• d1pgea2 appears in SCOPe 2.01
  
• d1pgea2 appears in the current release, SCOPe 2.08