SCOP 1.55: Domain d1a31a2: 1a31 A:215-430

Lineage for d1a31a2 (1a31 A:215-430)

1. Root: SCOP 1.55

2. Class e: Multi-domain proteins (alpha and beta) [56572] (28 folds)

3. Fold e.15: Eukaryotic DNA topoisomerase I, N-terminal DNA-binding fragment [56740] (1 superfamily)

4. Superfamily e.15.1: Eukaryotic DNA topoisomerase I, N-terminal DNA-binding fragment [56741] (1 family)

5. Family e.15.1.1: Eukaryotic DNA topoisomerase I, N-terminal DNA-binding fragment [56742] (1 protein)

6. Protein Eukaryotic DNA topoisomerase I, N-terminal DNA-binding fragment [56743] (2 species)

7. Species Human (Homo sapiens) [TaxId:9606] [56744] (4 PDB entries)

8. Domain d1a31a2: 1a31 A:215-430 [43263]
   Other proteins in same PDB: d1a31a1

Details for d1a31a2

PDB Entry: 1a31, 2.1 Å

PDB Description: human reconstituted dna topoisomerase i in covalent complex with a 22 base pair dna duplex

PDB Compounds: (A:) protein (topoisomerase I)

SCOP Domain Sequences for d1a31a2:

Sequence; same for both SEQRES and ATOM records:

>d1a31a2 e.15.1.1 (A:215-430) Eukaryotic DNA topoisomerase I, N-terminal DNA-binding fragment {Human (Homo sapiens)}
ikwkflehkgpvfappyeplpenvkfyydgkvmklspkaeevatffakmldheyttkeif
rknffkdwrkemtneekniitnlskcdftqmsqyfkaqtearkqmskeeklkikeenekl
lkeygfcimdnhkerianfkieppglfrgrgnhpkmgmlkrrimpediiincskdakvps
pppghkwkevrhdnkvtwlvswteniqgsikyimln

Timeline for d1a31a2:

• d1a31a2 appears in SCOP 1.57
  
• d1a31a2 appears in the current release, SCOPe 2.08