SCOPe 2.02: Domain d1rt4b_: 1rt4 B:

Lineage for d1rt4b_ (1rt4 B:)

1. Root: SCOPe 2.02

2. Class e: Multi-domain proteins (alpha and beta) [56572] (66 folds)

3. Fold e.8: DNA/RNA polymerases [56671] (1 superfamily)
   divided into morphological domains including "palm", "thumb" and "fingers"; the catalytic "palm" domain is conserved to all members

4. Superfamily e.8.1: DNA/RNA polymerases [56672] (6 families)
   "palm" domain has a ferredoxin-like fold, related to that of an adenylyl cyclase domain

5. Family e.8.1.2: Reverse transcriptase [56686] (3 proteins)

6. Protein HIV-1 reverse transcriptase [56689] (3 species)

7. Species Human immunodeficiency virus type 1 [TaxId:11676] [56690] (114 PDB entries)
   Uniprot P04585 159-692 # chain A coverage; chain B is shorter: 162-582 ! Uniprot P03366 186-725 # chain A coverage; chain B coverage: 156-584 ! Uniprot P04585 158-698 # chain A coverage; chain B is shorter: 159-595

8. Domain d1rt4b_: 1rt4 B: [43101]
   Other proteins in same PDB: d1rt4a1
   complexed with po4, uc1

Details for d1rt4b_

PDB Entry: 1rt4, 2.9 Å

PDB Description: hiv-1 reverse transcriptase complexed with uc781

PDB Compounds: (B:) hiv-1 reverse transcriptase

SCOPe Domain Sequences for d1rt4b_:

Sequence, based on SEQRES records:

>d1rt4b_ e.8.1.2 (B:) HIV-1 reverse transcriptase {Human immunodeficiency virus type 1 [TaxId: 11676]}
ietvpvklkpgmdgpkvkqwplteekikalveictemekegkiskigpenpyntpvfaik
kkdstkwrklvdfrelnkrtqdfwevqlgiphpaglkkkksvtvldvgdayfsvpldedf
rkytaftipsinnetpgiryqynvlpqgwkgspaifqssmtkilepfrkqnpdiviyqym
ddlyvgsdleigqhrtkieelrqhllrwglttpdkkhqkeppflwmgyelhpdkwtvqpi
vlpekdswtvndiqklvgklnwasqiypgikvrqlckllrgtkalteviplteeaelela
enreilkepvhgvyydpskdliaeiqkqgqgqwtyqiyqepfknlktgkyarmrgahtnd
vkqlteavqkittesiviwgktpkfklpiqketwetwwteywqatwipewefvntpplvk
lwyqlekep

Sequence, based on observed residues (ATOM records):

>d1rt4b_ e.8.1.2 (B:) HIV-1 reverse transcriptase {Human immunodeficiency virus type 1 [TaxId: 11676]}
ietvpvklkpgmdgpkvkqwplteekikalveictemekegkiskigpenpyntpvfaik
kkdstkwrklvdfrelnkrtqdfgiphpaglkkkksvtvldvgdayfsvpldedfrkyta
ftipsinnetpgiryqynvlpqgwkgspaifqssmtkilepfrkqnpdiviyqymddlyv
gsdleigqhrtkieelrqhllrwelhpdkwtvqpivlpekdswtvndiqklvgklnwasq
iypgikvrqlckllrgtkalteviplteeaelelaenreilkepvhgvyydpskdliaei
qkqgqgqwtyqiyqepfknlktgkyarmrgahtndvkqlteavqkittesiviwgktpkf
klpiqketwetwwteywqatwipewefvntpplvklwyqlekep

Timeline for d1rt4b_:

• d1rt4b_ first appeared (with stable ids) in SCOP 1.55, called d1rt4b1
  
• d1rt4b_ appears in SCOPe 2.01
  
• d1rt4b_ appears in SCOPe 2.03
  
• d1rt4b_ appears in the current release, SCOPe 2.08